Results 121 to 130 of about 10,041 (223)

Interaction of Related Tn916-Like Transposons: Analysis of Excision Events Promoted by Tn916 and Tn5386 Integrases

, 2006
In recent work, we described the excision of a large genomic region from Enterococcus faecium D344R in which the sequence from “joint ” regions suggested that excision resulted from the interaction of conjugative transposon Tn916 and the related mobile ...
Louis B. Rice, Lenore L. Carias, Susan Rudin, Rebecca Hutton-thomas   +3 more
core  

Real‐world use of second‐generation integrase strand transfer inhibitors (INSTI) as switch therapy in the prospective ANRS‐CO3‐AquiVIH‐NA cohort

HIV Medicine, Volume 27, Issue 6, Page 965-978, June 2026.
Abstract Objectives To characterize real‐world treatment switching in France to bictegravir (BIC or B) or dolutegravir (DTG)‐based regimens with a focus on treatment persistence, effectiveness (HIV‐1 RNA ≤50 copies/ml) and particular attention to the prevalence and incidence of comorbidities. Methods People living with HIV from the prospective ANRS‐CO3‐
O. Leleux, A. Peyrouny‐Mazeau, A. Perrier, M. Hessamfar, G. Le Moal, D. Neau, L. Alleman, C. Cazanave, E. Lazaro, P. Duffau, A. Riché, Y. Gérard, G. Barrière, S. Reigadas, M.‐A. Vandenhende, F. Bonnet   +15 more
wiley   +1 more source

Prevalence of Sleep Apnea and Sleepiness in Adults With and Without HIV in Mwanza, Tanzania: Baseline Results From an Ongoing Cohort Study

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT We conducted a cross‐sectional analysis of the baseline survey of participants aged > 30 years enrolled in the Mwanza HIV&CVD Cohort in Tanzania. Our primary objective was to examine the association between HIV status and sleep apnea (SA).
Godfrey A. Kisigo, Benson Issarow, Salama Fadhil, Grace Ruselu, Ponsiano Fabian, Ayubu Garbindi, Robert N. Peck, Kathy Baisley, Saidi Kapiga, Ana C. Krieger   +9 more
wiley   +1 more source

Phylogenetic structure and evolution of regulatory genes and integrases of P2-like phages

, 2011
The phylogenetic relationships and structural similarities of the proteins encoded within the regulatory region (containing the integrase gene and the lytic – lysogenic transcriptional switch genes) of P2-like phages were analyzed, and compared to the ...
Haggård-Ljungquist, Elisabeth, Anders S. Nilsson, Hanna Nilsson, Cardoso-Palacios, Carlos, Nilsson, Anders, Nilsson, Hanna, Carlos Cardoso-Palacios, Nilsson, Hanna,, Cardoso-Palacios, Carlos,, Haggård-Ljungquist, Elisabeth,, Elisabeth Haggård-Ljungquist, Nilsson, Anders,   +11 more
core   +1 more source

A Natural LTR Retrotransposon Insertion in the Promoter of GhNAC140‐Dt Boosts Cotton Lint Yield

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4240-4262, June 2026.
ABSTRACT Transposable elements (TEs) are fundamental drivers of crop evolution and domestication. Whereas the underlying mechanisms of TE‐mediated gene activation remain poorly understood. Lint percentage is an important yield component in cotton. Here, we report a retrotransposon insertion in the promoter of GhNAC140‐Dt, a secondary wall NAC encoding ...
Yujia Yu, Xiaoguang Shang, Haitang Wang, Lijie Zhu, Xu Han, Qingfei He, Weixi Li, Yonglin Tan, Guozhong Zhu, Wangzhen Guo   +9 more
wiley   +1 more source

vB_CacS-HV1 as a Novel Pahexavirus Bacteriophage with Lytic and Anti-Biofilm Potential against Cutibacterium acnes

Microorganisms
Acne vulgaris is a prevalent chronic inflammatory skin disease, most common in adolescence and often persisting into adulthood, leading to severe physical and psychological impacts. The primary etiological factor is Cutibacterium acnes infection.
Xu Li, Wenyan Ding, Zicheng Li, Yi Yan, Yigang Tong, Jialiang Xu, Mengzhe Li   +6 more
doaj   +1 more source

Serine integrases as a toolbox for genome editing

, 2017
The development of a biological production platform for specialty chemicals requires on the one hand a profound knowledge of the organism’s genomics, its metabolism, and even its system biology, and on the other hand the availability of tools for small ...
De Mol, Maarten, Snoeck, Nico, De Maeseneire, Sofie, Van Herpe, Dries, Beauprez, Joeri, Soetaert, Wim   +5 more
core  

DJ: Tdd-4, a DNA transposon of Dictyostelium that encodes proteins similar to LTR retroelement integrases

, 1999
Tdd-4 is the first DNA transposon to be isolated from Dictyostelium discoideum. This element was isolated by insertion into a target plasmid. Two classes of elements were identified which include a 3.8 kb version and a 3.4 kb deleted version.
David J. Wells
core  

In vitro analysis of the susceptibility of HIV-1 subtype A and CRF01_AE integrases to raltegravir.

, 2014
International audienceThe antiviral efficacy of raltegravir (RAL) has been proven against human immunodeficiency virus type 1 (HIV-1) subtypes B and C but remained to be determined against other subtypes.
Andreola, Marie-Line, Parissi, Vincent, Malato, Laurent, Reigadas, Sandrine, Fleury, Hervé, Calmels, Christina, Bellecave, Pantxika   +6 more
core   +1 more source

A rat brain mRNA encoding a transcriptional activator homologous to the DNA binding domain of retroviral integrases.

, 1991
We have isolated a rat cDNA, named FE65, hybridizing to an mRNA of about 2,300 nucleotides present in rat brain, undetectable in rat liver and very poorly represented in other tissues.
Cimino F, DUILIO, ANGELA, AMMENDOLA, ROSARIO, ZAMBRANO, NICOLA, Mogavero AR, RUSSO, TOMMASO   +5 more
core