Results 131 to 140 of about 18,910 (292)
HIV Medicine, EarlyView.Abstract Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking. Integrase inhibitor (INI) resistance may limit future therapy.
Kyle Ring +4 more
wiley +1 more source
Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]
, 2016 American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S. +4 more
core +2 more sources
A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein [PDF]
, 1994 Cornelis Vink +3 more
openalex +1 more source
HIV Medicine, EarlyView.Abstract Introduction: Human immunodeficiency virus‐1 (HIV‐1) continues to have a high global burden, with approximately 39.9 million people currently living with the virus. Despite the clinical success of antiretroviral therapy (ART), adherence remains a significant challenge, often due to emotional distress and HIV‐related stigma.
Dhruv Vinay +3 more
wiley +1 more source
Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations [PDF]
, 1993 Karen A. Vincent +3 more
openalex +1 more source
Significance of constitutive integrase synthesis. [PDF]
Proceedings of the National Academy of Sciences, 1976 One conceivable function for constitutive integrase formation by lambda prophage is to stabilize the inserted state by catalyzing reinsertion of prophages that are accidentally excised. As this hypothesis implies a dynamic equilibrium betwen inserted and noninserted DNA, the existence of such an equilibrium is explored.
openaire +3 more sources
HIV Medicine, EarlyView.Abstract Introduction Women remain underrepresented in studies on immunological response (IR) among virally suppressed people living with HIV. Despite receiving antiretroviral therapy (ART) some individuals do not attain an IR, increasing their risk of non‐AIDS morbidity and mortality.
Josefin Nilsson +6 more
wiley +1 more source
Conserved residues Pro-109 and Asp-116 are required for interaction of the human immunodeficiency virus type 1 integrase protein with its viral DNA substrate [PDF]
, 1993 Meera Drelich, Markus Haenggi, Jan Mous
openalex +1 more source
Effectiveness of switching to doravirine‐based antiretroviral therapy: A real‐world study in Germany
HIV Medicine, EarlyView.Abstract Objectives Doravirine (DOR)‐based antiretroviral therapy (ART) has been shown in clinical trials to be effective and well tolerated in treating HIV‐1. The EffectiVeness of SwItChing to DORavirine‐based Antiretroviral Therapy (VICDOR) study characterized the use, effectiveness and impact on body weight and lipids of DOR‐based ART in a ...
Christoph Wyen +12 more
wiley +1 more source
Frontiers in Microbiology, 2015 The seed as a habitat for microorganisms is as yet under-explored and has quite distinct characteristics as compared to other vegetative plant tissues. In this study, we investigated three closely related P.
Raheleh eSheibani-Tezerji +6 more
doaj +1 more source