Results 61 to 70 of about 31,694 (314)

Integron Integrases Possess a Unique Additional Domain Necessary for Activity [PDF]

Journal of Bacteriology, 2001
Nancy Messier, Paul H. Roy
openalex   +2 more sources

Lambda Integrase: Armed for Recombination [PDF]

Current Biology, 2005
Bacteriophage lambda moves its viral genome into and out of the bacterial chromosome using site-specific recombination. Crystal structures of reaction intermediates in this recombination pathway provide exciting new snapshots of full length lambda integrase interacting with both core and regulatory DNA elements.
openaire   +3 more sources

A snapshot on HIV-1 evolution through the identification of phylogenetic-specific properties of HIV-1 integrases M/O

PLoS Pathogens, 2023
Transmissions of simian viruses to humans has originated the different groups of HIV-1. We recently identified a functional motif (CLA), in the C-terminal domain of the integrase, essential for integration in HIV-1 group M.
Elenia Toccafondi, Marine Kanja, Flore Winter, Daniela Lener, Matteo Negroni   +4 more
doaj   +2 more sources

Metagenomic community composition and resistome analysis in a full-scale cold climate wastewater treatment plant

Environmental Microbiome, 2022
Background Wastewater treatment plants are an essential part of maintaining the health and safety of the general public. However, they are also an anthropogenic source of antibiotic resistance genes.
Paul Jankowski, Jaydon Gan, Tri Le, Michaela McKennitt, Audrey Garcia, Kadir Yanaç, Qiuyan Yuan, Miguel Uyaguari-Diaz   +7 more
doaj   +1 more source

Cluster J Mycobacteriophages: Intron Splicing in Capsid and Tail Genes [PDF]

, 2013
Bacteriophages isolated on Mycobacterium smegmatis mc2155 represent many distinct genomes sharing little or no DNA sequence similarity. The genomes are architecturally mosaic and are replete with genes of unknown function.
Best, AA, Broussard, GW, Connerly, PL, Conway, JF, Dedrick, RM, Hatfull, GF, Hendrix, RW, Jacobs-Sera, D, Kremer, TA, Offner, S, Ogiefo, AH, Pizzorno, MC, Pope, WH, Rockenbach, K, Russell, DA, Stowe, EL, Stukey, J, Thibault, SA   +17 more
core   +4 more sources

A novel family of tyrosine integrases encoded by the temperate pleolipovirus SNJ2

Nucleic Acids Research, 2018
Genomes of halophilic archaea typically contain multiple loci of integrated mobile genetic elements (MGEs). Despite the abundance of these elements, however, mechanisms underlying their site-specific integration and excision have not been investigated ...
Jiao Wang, Yingchun Liu, Ying Liu, Kaixin Du, Shuqi Xu, Yuchen Wang, M. Krupovic, Xiangdong Chen   +7 more
semanticscholar   +1 more source

Tangle Solutions for a Family of DNA-Rearranging Proteins [PDF]

, 2004
We study two systems of tangle equations that arise when modeling the action of the Integrase family of proteins on DNA. These two systems--direct and inverted repeats--correspond to two different possibilities for the initial DNA sequence. We present one new class of solutions to the tangle equations.
arxiv   +1 more source

Transcriptome analysis of bacteriophage communities in periodontal health and disease. [PDF]

, 2015
BackgroundThe role of viruses as members of the human microbiome has gained broader attention with the discovery that human body surfaces are inhabited by sizeable viral communities.
Abeles, Shira R, Boehm, Tobias K, Ly, Melissa, Naidu, Mayuri, Pride, David T, Santiago-Rodriguez, Tasha M   +5 more
core   +2 more sources

The role of single occupancy effects on integrase dynamics in a cell-free system [PDF]

, 2016
Phage integrase-based circuits are an alternative approach to relying on transcriptional and translational repression for biomolecular circuits. Previous research has shown that circuits based on integrases can perform a variety of functions, including ...
Artavanis, Georgios, Hayes, Clarmyra A., Hsiao, Victoria, Murray, Richard M.   +3 more
core   +1 more source

Genomic and Functional Characterization of Vancomycin-Resistant Enterococci-Specific Bacteriophages in the Galleria mellonella Wax Moth Larvae Model

Pharmaceutics, 2022
Phages are naturally occurring viruses that selectively kill bacterial species without disturbing the individual’s normal flora, averting the collateral damage of antimicrobial usage.
Lynn El Haddad, Georgios Angelidakis, Justin R. Clark, Jesus F. Mendoza, Austen L. Terwilliger, Christopher P. Chaftari, Mark Duna, Serena T. Yusuf, Cynthia P. Harb, Mark Stibich, Anthony Maresso, Roy F. Chemaly   +11 more
doaj   +1 more source