Results 81 to 90 of about 10,041 (223)

Dispersion of Phage Integrases in Acinetobacter Baumannii Species

open access: yes, 2014
Dispersion of Phage Integrases in Acinetobacter baumannii strains E. Stephanie Guardado1,2, German M. Traglia2, Dr. M. Soledad Ramirez2 1Biological Sciences Dept, Cal Poly Pomona 2Instituto de Microbiolog??a y Parasitolog??a Medica (IMPaM), Facultad de ...
Guardado, Eleana
core   +1 more source

Potential unlocked: an atlas of cloned wheat genes for genome engineering and breeding

open access: yesNew Phytologist, EarlyView.
Strategies for introducing genome edits into a wheat breeding program and their effects on cultivar longevity. Summary Bread wheat (Triticum aestivum) production is increasingly threatened by biotic and abiotic stresses. Developing varieties with improved stress tolerance and desirable end‐use qualities is crucial for meeting growing global demand ...
Abdulrahman Alhabsi   +7 more
wiley   +1 more source

DNA synapsis and cleavage assays with wild-type and mutant integrases.

open access: yes, 2013
Labelled attB was incubated with wild-type or mutant integrases (Panel A:R18A, I141A; Panel B:L143A, E153A; Panel C:I432A) in the presence of no cold attP, 198 bp cold attP in binding buffer and then untreated or treated with proteinase K. Reactions were
Siman Peng (367675)   +7 more
core   +1 more source

Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 74-88, July 2026.
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani   +14 more
wiley   +1 more source

In silico analysis of integrases in the phytopathogen Xylella fastidiosa: diversity, integration sites and association with bacteriophages.

open access: yes, 2008
Os elementos genéticos móveis encontrados no genoma da bactéria Xylella fastidiosa (Xf) são representados principalmente por bacteriófagos (na forma de profagos inseridos no genoma) e ilhas genômicas.
Varani, Alessandro de Mello   +1 more
core   +1 more source

A simplified mathematical model of directional DNA site-specific recombination by serine integrases [PDF]

open access: yes, 2016
Serine integrases catalyse site-specific recombination to integrate and excise bacteriophage genomes into and out of their host's genome. These enzymes exhibit remarkable directionality; in the presence of the integrase alone, recombination between attP ...
Stark, W. Marshall   +4 more
core   +1 more source

Lambda Integrase: Armed for Recombination [PDF]

open access: yesCurrent Biology, 2005
Bacteriophage lambda moves its viral genome into and out of the bacterial chromosome using site-specific recombination. Crystal structures of reaction intermediates in this recombination pathway provide exciting new snapshots of full length lambda integrase interacting with both core and regulatory DNA elements.
openaire   +2 more sources

Nickel Photocatalytic Access to β‐Arylated β‐Amino Acids

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
Converting naturally abundant amino acids to non‐canonical derivatives in one step under mild conditions allows for improved pharmaceutical properties. Now, this is achieved for β‐arylated β‐amino acids, which are available in good yields directly from aspartic acid, and have the potential to become platform chemicals for drug discovery.
Tim S. Stamp   +3 more
wiley   +1 more source

Activity assay for purified integrases.

open access: yes
(A) Purified integrases (C3, C6, C7) were incubated with indicated plasmid DNA substrates and activity determined by real-time PCR using the primer 5 + 6 pair. Reactions comprised 17nM integrase and 1.3nM respective DNA substrate.
Srinivasaraghavan Kannan (463594)   +8 more
core   +1 more source

Transcription Factor YY1 Interacts with Retroviral Integrases and Facilitates Integration of Moloney Murine Leukemia Virus cDNA into the Host Chromosomes

open access: yes, 2010
Retroviral integrases associate during the early viral life cycle with preintegration complexes that catalyze the integration of reverse-transcribed viral cDNA into the host chromosomes.
Yuya Kinoshita   +12 more
core   +1 more source

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