Results 81 to 90 of about 10,041 (223)
Dispersion of Phage Integrases in Acinetobacter Baumannii Species
Dispersion of Phage Integrases in Acinetobacter baumannii strains E. Stephanie Guardado1,2, German M. Traglia2, Dr. M. Soledad Ramirez2 1Biological Sciences Dept, Cal Poly Pomona 2Instituto de Microbiolog??a y Parasitolog??a Medica (IMPaM), Facultad de ...
Guardado, Eleana
core +1 more source
Potential unlocked: an atlas of cloned wheat genes for genome engineering and breeding
Strategies for introducing genome edits into a wheat breeding program and their effects on cultivar longevity. Summary Bread wheat (Triticum aestivum) production is increasingly threatened by biotic and abiotic stresses. Developing varieties with improved stress tolerance and desirable end‐use qualities is crucial for meeting growing global demand ...
Abdulrahman Alhabsi +7 more
wiley +1 more source
DNA synapsis and cleavage assays with wild-type and mutant integrases.
Labelled attB was incubated with wild-type or mutant integrases (Panel A:R18A, I141A; Panel B:L143A, E153A; Panel C:I432A) in the presence of no cold attP, 198 bp cold attP in binding buffer and then untreated or treated with proteinase K. Reactions were
Siman Peng (367675) +7 more
core +1 more source
Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani +14 more
wiley +1 more source
Os elementos genéticos móveis encontrados no genoma da bactéria Xylella fastidiosa (Xf) são representados principalmente por bacteriófagos (na forma de profagos inseridos no genoma) e ilhas genômicas.
Varani, Alessandro de Mello +1 more
core +1 more source
A simplified mathematical model of directional DNA site-specific recombination by serine integrases [PDF]
Serine integrases catalyse site-specific recombination to integrate and excise bacteriophage genomes into and out of their host's genome. These enzymes exhibit remarkable directionality; in the presence of the integrase alone, recombination between attP ...
Stark, W. Marshall +4 more
core +1 more source
Lambda Integrase: Armed for Recombination [PDF]
Bacteriophage lambda moves its viral genome into and out of the bacterial chromosome using site-specific recombination. Crystal structures of reaction intermediates in this recombination pathway provide exciting new snapshots of full length lambda integrase interacting with both core and regulatory DNA elements.
openaire +2 more sources
Nickel Photocatalytic Access to β‐Arylated β‐Amino Acids
Converting naturally abundant amino acids to non‐canonical derivatives in one step under mild conditions allows for improved pharmaceutical properties. Now, this is achieved for β‐arylated β‐amino acids, which are available in good yields directly from aspartic acid, and have the potential to become platform chemicals for drug discovery.
Tim S. Stamp +3 more
wiley +1 more source
Activity assay for purified integrases.
(A) Purified integrases (C3, C6, C7) were incubated with indicated plasmid DNA substrates and activity determined by real-time PCR using the primer 5 + 6 pair. Reactions comprised 17nM integrase and 1.3nM respective DNA substrate.
Srinivasaraghavan Kannan (463594) +8 more
core +1 more source
Retroviral integrases associate during the early viral life cycle with preintegration complexes that catalyze the integration of reverse-transcribed viral cDNA into the host chromosomes.
Yuya Kinoshita +12 more
core +1 more source

