Results 81 to 90 of about 10,473 (233)

Contribution of plasmidome, metal resistome and integrases to the persistence of the antibiotic resistome in aquatic environments

, 2022
Wastewater treatment plants (WWTPs) are among the main hotspots of antibiotic resistance genes (ARGs) in the environment. Previously, we demonstrated that, by increasing anthropogenic pollution, the antibiotic resistome persisted in the microbial ...
Pu Li, Diego Brambilla, Andrea Di Cesare, Raffaella Sabatino, Diego Fontaneto, Gianluca Corno, Ying Yang, Ester M Eckert   +7 more
core   +1 more source

UltRaSoUnd‐guided evaLuAtion of metabolic health in a cohort of midlife women with HIV: The URSULA study

HIV Medicine, EarlyView.
Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno, Davide Capruzzi, Antonio Cianciaruso, Nicola Colavito, Felicia Dalitto, Vincenzo Giliberti, Vittoria Lobalsamo, Giuliana Metrangolo, Marica Noviello, Alessandra Vigna, Maurizio Zarcone, Francesco Di Gennaro, Vincenzo Ostilio Palmieri, Annalisa Saracino   +13 more
wiley   +1 more source

Semaglutide improves MASLD and MASH in people with HIV: The SLIM LIVER study

HIV Medicine, EarlyView.
Abstract Objectives We have shown that semaglutide, a glucagon‐like peptide‐1 receptor agonist (GLP‐1RA), is a highly effective therapy for metabolic dysfunction‐associated steatotic liver disease (MASLD) in people with HIV (PWH). The OWLiver® metabolomics algorithms allow non‐invasive MASLD severity staging without liver biopsy, but the use of ...
Jordan E. Lake, Douglas W. Kitch, Amy Kantor, Rebeca Mayo, Pablo Belaunzaran‐Zamudio, Carl J. Fichtenbaum, Todd T. Brown, Kathleen E. Corey, Fred Sattler, Kristine M. Erlandson   +9 more
wiley   +1 more source

Characteristics and management of low‐level viraemia in people living with HIV in a resource‐limited setting: A multicentre retrospective study in Greece

HIV Medicine, EarlyView.
Abstract Objectives Low‐level viraemia (LLV) persists in some people living with HIV despite antiretroviral therapy, raising concerns about virologic failure. We assessed the characteristics, management and outcomes of LLV in Greece, where next‐generation sequencing, therapeutic drug monitoring and electronic adherence monitoring are unavailable ...
Lydia Leonidou, Giota Lourida, Konstantinos Protopapas, Charalampos D. Moschopoulos, Dimitrios Zoulas, Charisis Totsikas, Dimitrios Basoulis, Elpida Mastrogianni, Apostolos Beloukas, Maria Lagadinou, Markos Marangos, Vasileios Papastamopoulos, Antonios Papadopoulos, Mina Psichogiou   +13 more
wiley   +1 more source

Activity assay for purified integrases.

(A) Purified integrases (C3, C6, C7) were incubated with indicated plasmid DNA substrates and activity determined by real-time PCR using the primer 5 + 6 pair. Reactions comprised 17nM integrase and 1.3nM respective DNA substrate.
Srinivasaraghavan Kannan (463594), Sabrina Peter (2102437), Jia Wei Siau (17959248), Asim Azhar Siddiqui (6060770), John F. Ghadessy (17959257), Peter Droge (17959254), Sze Yi Lau (17959251), Chandra Verma (23219), Yingying Zeng (2122864)   +8 more
core   +1 more source

Frailty and associated clinical factors among Japanese people with HIV: A multicentre cross‐sectional study using the revised Japanese Cardiovascular Health Study criteria

HIV Medicine, EarlyView.
Abstract Objectives Frailty is relevant to HIV care across middle and later life, yet Japanese data remain limited. We evaluated frailty, prefrailty and associated factors in Japanese people with HIV using the revised Japanese Cardiovascular Health Study (J‐CHS) criteria.
Hideta Nakamura, Julian Falutz, Taro Naka, Sho Miyamori, Nanae Ikemiyagi, Kazutaka Yamaniha, Shuhei Ideguchi, Rumi Minami, Masashi Narita, Michinori Shirano, Sei Samukawa, Tomoyuki Endo, Junji Imamura, Mayumi Imahashi, Shinichiro Ueda, Kazuko Yamamoto   +15 more
wiley   +1 more source

Dietary counselling and exercise training for lipid management in people living with HIV: A systematic review and meta‐analysis

HIV Medicine, EarlyView.
Abstract Objectives Dyslipidaemia is highly prevalent among people living with human immunodeficiency virus (HIV) and contributes to increased cardiovascular risk. Although lifestyle interventions are recommended, evidence specific to people living with HIV remains limited. Previous reviews have primarily focused on dietary interventions or low‐density
Maki Aomori, Hitomi Maeda
wiley   +1 more source

Venezuelan migrants living with HIV in Barcelona: Migration patterns and baseline immunovirological characteristics in a retrospective cohort study

HIV Medicine, EarlyView.
Abstract Objectives To describe the sociodemographic characteristics, migration patterns and immunovirological outcomes of Venezuelan migrants living with HIV (PLWH) in Barcelona, Spain, and to compare them with other Latin American (LA) migrant PLWH. Methods We conducted a retrospective observational cohort study including LA migrant PLWH who attended
Alexy Inciarte, Elizabeth Zamora‐Clemente, Leire Berrocal, Ana González‐Cordón, Lorena De La Mora, María Martínez‐Rebollar, Montserrat Laguno, Juan Ambrosioni, Iván Chivite, Elisa de Lazzari, Alberto Foncillas, Júlia Calvo, Abiu Sempere, Esteban Martínez, José M. Miró, José Luis Blanco, Berta Torres, Josep Mallolas   +17 more
wiley   +1 more source

Secondary structure estimation from CD spectra of wild-type and mutant phiC31 integrases.

, 2013
Secondary structure estimation from CD spectra of wild-type and mutant phiC31 integrases.
Siman Peng (367675), Huanzhang Zhu (123147), Jinfang Ma (38894), Maoxiang Zhang (367671), Rongxiu Li (139385), Shaohui Liu (367669), Wei Wang (17594), Qingting Xin (367673)   +7 more
core   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source