Results 51 to 60 of about 4,556 (294)
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
Reconfigurable Hardware-in-the-Loop Test Bench for the SHEFEX2 Hybrid Navigation System Experiment
The Hybrid Navigation System is being developed to achieve the required attitude accuracy and calculate a navigation solution for the SHEFEX2 mission, which will be launched in February 2012 from And\o ya Rocket Range in Norway by the German Aerospace ...
Steffes, Stephen R. +7 more
core +1 more source
The autonomous vehicular navigation technology has gained more and more attention of researchers. Odometer is the most commonly used auxiliary sensor for autonomous navigation in vehicles due to its stability and high accuracy.
Shuang Pan +3 more
doaj +1 more source
Integrated navigation for autonomous underwater vehicles in aquaculture: A review
Aquaculture is the world’s fastest growing sector within the food industry, supplying humans with over half their aquatic products. Water quality monitoring or cage inspection is an indispensable part in aquaculture and is usually done manually ...
Jianhua Bao +3 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
PDR/INS/WiFi Integration Based on Handheld Devices for Indoor Pedestrian Navigation
Providing an accurate and practical navigation solution anywhere with portable devices, such as smartphones, is still a challenge, especially in environments where global navigation satellite systems (GNSS) signals are not available or are degraded ...
Yuan Zhuang +3 more
doaj +1 more source
Design of Accurate Navigation System by Integrating INS and GPS modules [PDF]
Navigation has a huge application in aviation and aircraft automatic approach. Two widely used navigation systems are Global position System (GPS) and Inertial Navigation System (INS). Triangulation method used to determine the aircrafts location by GPS,
M. RAJA +4 more
doaj +1 more source

