Results 61 to 70 of about 140,474 (263)

Harnessing optical micro-combs for microwave photonics

, 2018
In the past decade, optical frequency combs generated by high-Q micro-resonators, or micro-combs, which feature compact device footprints, high energy efficiency, and high-repetition-rates in broad optical bandwidths, have led to a revolution in a wide ...
Chu, Sai Tak, Little, Brent E., Mitchell, Arnan, Morandotti, Roberto, Moss, David J., Moss, DJ (reprint author), Swinburne Univ Technol, Ctr Microphoton, Hawthorn, Vic 3122, Australia., Nguyen, Thach G., Wu, Jiayang, Xu, Xingyuan   +8 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Analysis, Design, and Implementation of Improved LLC Resonant Transformer for Efficiency Enhancement

Energies, 2018
In battery charging applications, the charger changes its output voltage in a wide range during the charging process. This makes the design of LLC converters difficult to be optimized between the efficiency and the gain range.
Zhenxing Zhao, Qianming Xu, Yuxing Dai, Hanhang Yin   +3 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integrated linear reactor in transformer based on non-orthogonal decoupling method

Energy Reports, 2020
The air-core reactor has the advantage of good linearity and low noise, however the problem of large space occupation. Power filter with the air-core reactor is indispensable with the widespread use of the power electronic devices in electrified ...
Jinwen Xiang, Zhidong Yang, Longfu Luo, Nihan Tong, Chaowei Han, Shengjie Yang   +5 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Mitigation of voltage sag, swell and power factor correction using solid-state transformer b

Alexandria Engineering Journal, 2014
This paper presents a novel topology of solid-state transformer (SST). In the design process, the AC/DC, DC/AC and AC/AC converters have been integrated to achieve higher efficiency. To obtain higher efficiency from other SST with DC-link topologies, the
M.R. Banaei, E. Salary
doaj   +1 more source

Smart grids for rural conditions and e-mobility - Applying power routers, batteries and virtual power plants [PDF]

, 2016
Significant reductions of greenhouse gas emission by use of renewable energy sources belong to the common targets of the European Union. Smart grids address intelligent use and integration of conventional and renewable generation in combination with ...
Boehner, Volker, Franz, P., Gallart, R, Girbau Llistuella, Francesc, Hanson, J., Martínez, S., Sumper, Andreas   +6 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source