Results 151 to 160 of about 317,716 (343)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Integrin-linked Kinase Controls Neurite Outgrowth in N1E-115 Neuroblastoma Cells [PDF]

, 2001
Toshiaki Ishii, Eiki Satoh, Masakazu Nishimura   +2 more
openalex   +1 more source

Supplementary Figure 2 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

, 2023
Huimin Lu, Tao Wang, Jing Li, Carmine Fedele, Qin Liu, Jianzhong Zhang, Jiang Zhong, Dhanpat Jain, Renato V. Iozzo, Shelia M. Violette, Paul H. Weinreb, Roger J. Davis, Daniel Gioeli, Thomas J. FitzGerald, Dario C. Altieri, Lucia R. Languino   +15 more
openalex   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Shedding of heterodimeric leukocyte integrin [PDF]

, 2006
Martin E. Hemler
openalex   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Eptifibatide and 7E3, but Not Tirofiban, Inhibit α _v β ₃ Integrin–Mediated Binding of Smooth Muscle Cells to Thrombospondin and Prothrombin [PDF]

, 2002
Robert M. Scarborough
openalex   +1 more source

A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening

Advanced Materials, EarlyView.
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder, Nergishan İyisan, Yukun Wang, Berna Özkale   +3 more
wiley   +1 more source

Corrigendum: Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model

Frontiers in Pharmacology
Wen Zhou, Han Qu, Xiao-Xiao Fu, Miao-Miao Xu, Qiang Li, Yuan Jiang, Shu Han   +6 more
doaj   +1 more source

Decoding collagen cues: the interplay of integrins and discoidin domain receptors in health and disease. [PDF]

J Biomed Sci
Trono P, Masi I, Ottavi F, Rosanò L.
europepmc   +1 more source