Results 261 to 270 of about 245,645 (318)

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

No association between the wearing-off effect and α4-integrin receptor saturation in natalizumab treated patients with relapsing-remitting multiple sclerosis. [PDF]

Neurotherapeutics
Freeman SA, Rual C, Biotti D, Lepetit M, Le Berre J, Ferrara K, Treiner E, Ciron J.   +7 more
europepmc   +1 more source

A proximity-labeling map of PI5P4K phosphoinositide kinases interaction networks. [PDF]

J Biol Chem
Llorente A, Arora GK, Loughran RM, Murad R, Maurya S, Crabtree S, Portillo B, Chapagain P, Huluka H, Eron S, Goodman K, Ye G, Blind RD, Emerling BM.   +13 more
europepmc   +1 more source

Hemidesmosomes and Notch signaling regulate epidermal differentiation via delamination. [PDF]

Development
King JS, Lough KJ, Williams SE.
europepmc   +1 more source

Cathepsin Z/X: Breaking Down the Known and Unknown. [PDF]

Int J Mol Sci
Zdravkova K, Pavicević M, Mijanović O, Branković A, Ilicheva PM, Stankovski A, Karanović J, Pualić D, Rubel AA, Rodionov IV, Savvateeva LV, Parodi A, Zamyatnin AA.   +12 more
europepmc   +1 more source

Elevated neuraminidase potentiates lung inflammation through facilitating integrin β2-mediated adhesion and immune responses of neutrophils. [PDF]

J Biol Chem
Huang L, Tang A, Zhong H, Liang Y, Shao B.   +4 more
europepmc   +1 more source

Mannose-binding lectin 2 secreted by hepatocellular carcinoma cells recruits and activates natural killer cells to reshape an immune-activated microenvironment. [PDF]

PLoS Biol
Liao H, Yang J, Cai L, Chi L, Wang C, Xu Y, Xie J, Chen K, Pei J, Jiang Z, Pan M, Zhao L.   +11 more
europepmc   +1 more source

Identification and structural characterisation of a picornavirus integrin receptor with an essential role of two distinct glycans for virus infection

Kuppeveld Fv, Owino C, Dellosa G, Luteijn R, Zwaagstra M, Yu X, Eecke JV, Buitenwerf F, Meijer W, Liu M, de Haan C, Hurdiss D, Porta C, Duyvesteyn H, Kelly J, Tuthill T, Narimatsu Y, Clausen H, Shah P, Fry E, Reiding K, de Vries E, Stuart D.   +22 more
europepmc   +1 more source

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Integrins and Disease

Clinical Science, 1996
1. Adhesion is a vital property of cells. It provides a stable environment for cell growth and differentiation and allows cells to migrate. 2. The interaction between cells and their extracellular matrices is also an important factor in the regulation of further protein deposition.
G S, Hillis, A M, MacLeod
openaire   +2 more sources