Results 151 to 160 of about 234,137 (355)
Journal of Cancer, 2019 Background: Glucose transporter 1 (GLUT1) is the main factor of Warburg effect, which is associated with poor prognosis in many tumors. However, the underlying molecular mechanism of GLUT1 in the progression of non-small cell lung cancer (NSCLC) is ...
Huanyu Zhao +6 more
semanticscholar +1 more source
Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity [PDF]
, 2019 Macrophages resident in different organs express distinct genes, but understanding how this diversity fits into tissue-specific features is limited. Here, we show that selective expression of coagulation factor V (FV) by resident peritoneal macrophages ...
Broze, George J +12 more
core +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
Advanced Science, EarlyView.This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim +12 more
wiley +1 more source
International Journal of Oncology, 2016 Chemotherapeutic failure and metastasis are the main causes of high mortality rate in lung cancer. Alteration of cellular redox status in response to endogenous stimuli or exogenous compounds has a significant impact on cell signaling and behavior ...
Punyawee Puchsaka +2 more
semanticscholar +1 more source
Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6
Advanced Science, EarlyView.Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee +3 more
wiley +1 more source
Chinese Journal of Lung Cancer, 2009 Background and objective As invasion and metastasis of cancer seriously threaten human's life, it is of more important clinical significance to understand and evaluate the biologic behavior of cancer correctly.
Zhidong LIU +4 more
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Scientific Reports, 2015 Collective cell migration plays a crucial role in several biological processes, such as embryonic development, wound healing and cancer metastasis. Here, we focused on collectively migrating Madin-Darby Canine Kidney (MDCK) epithelial cells that follow a
Naoya Yamaguchi +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang +11 more
wiley +1 more source
Biochemistry and Biophysics Reports, 2021 The surface of the human respiratory tract is covered with a mucus layer containing mucin 5AC (MUC5AC) and mucin 5B (MUC5B) as the main components. This layer contributes to biological defense by eliminating irritants, but excessive MUC5AC secretion by ...
Jun Iwashita, Jun Murata
doaj
OncoTarget, 2017 Recent studies have reported that CTS can alleviate cardiac fibrosis. However, the effects of CTS on kidney fibrosis and EMT are still unknown. This study explored whether CTS could attenuate tubulointerstitial fibrosis as well as EMT, and investigated ...
W. Wang +6 more
semanticscholar +1 more source