Results 171 to 180 of about 145,582 (257)

Disruption of thrombospondin 1/2-integrin β1 axis impairs cell adhesion and tumor growth in intrahepatic cholangiocarcinoma. [PDF]

Cell Death Discov
Porreca V, Giancola L, Sallustio L, Conigliaro A, Angelone P, Marrone R, Greco F, Giangrande DM, Bontempi G, Stella M, Palmisano B, Mignogna G, Meucci M, Melandro F, Mennini G, Rossi M, Riminucci M, Corsi A, Stabile H, Ragusa M, Filippini A, Fulci V, Strippoli R, Maras B, Mancone C.   +24 more
europepmc   +1 more source

Engineering In Vitro Models of Skeletal Muscle With Neuromuscular Junctions Using Hierarchical Micro‐Nano Biomaterials: Cooperative Effect of Adhesion Ligand Nanoclustering and Surface Anisotropy

Small, EarlyView.
This study investigates the cooperative effects of adhesive ligand distribution, density, and biomaterial morphology for innervated skeletal muscle tissue engineering. Ligand nanoclusters were created in aligned micropatterns by electrospinning of a RAFT‐synthesized polymer with controlled ligand presentation.
Shirin Nour, Kristy Swiderski, Sahar Salehi, Gordon S. Lynch, Andrea J. O'Connor, Greg G. Qiao, Daniel E. Heath   +6 more
wiley   +1 more source

Exosome Nanotherapy Rescues Male Fertility by Delivering Integrin β1 to Repair Environmental Stress-Damaged Testes. [PDF]

Mol Pharm
Meng J, Wang J, Li Z, Li F, Yun X, Jin Y, Zhang L.   +6 more
europepmc   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Highly branched complex-type N-glycans on integrin β1 in extracellular vesicles enhance the binding of sEVs to laminin on recipient cells. [PDF]

J Biol Chem
Isogai T, Tokoro Y, Nakano M, Hirosawa KM, Kasai RS, Yokota Y, Kizuka Y, Suzuki KGN.   +7 more
europepmc   +1 more source

Engineering Carbon Nanotube Quantum Well Defects With Recognition Tripeptides for Optical Detection of Extracellular Vesicles in Plasma

Small, EarlyView.
A three‐residue peptide bioconjugated onto a carbon nanotube quantum defect turns the near‐infrared emission of quantum defects into a reporter of integrins on intact extracellular vesicles, directly in human plasma. The sensor reveals that healthy fibroblast vesicles carry as much RGD‐binding integrin as cancer‐derived ones, an adhesion‐associated ...
In‐Jun Hwang, Junhee Kim, Aarti Patel, Leilei Zhang, Jacob Miller, Stanislav Piletsky, Cassandra L. Clift, Colin Hisey, YongJoo Kim, Mijin Kim   +9 more
wiley   +1 more source

Integrin β1 Demarks Precursors of Brain-Residing Antibody-Secreting Cells in Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Kuiper KL, Bogers L, Rip J, van Hasselt Y, Melief MJ, Wierenga-Wolf AF, Klein Kranenbarg RAM, Bindels E, van de Werken HJG, de Beukelaar J, Smets I, Wokke B, Smolders J, van Luijn MM.   +13 more
europepmc   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

Phosphomimetic Thrombospondin-1 Modulates Integrin β1-FAK Signaling and Vascular Cell Functions. [PDF]

Biomolecules
Raya A, Bécsi B, Boratkó A.
europepmc   +1 more source

PACSIN2 regulates platelet integrin β1 hemostatic function. [PDF]

J Thromb Haemost, 2023
Biswas R, Boyd EK, Eaton N, Steenackers A, Schulte ML, Reusswig F, Yu H, Drew C, Kahr WHA, Shi Q, Plomann M, Hoffmeister KM, Falet H.   +12 more
europepmc   +1 more source