Results 211 to 220 of about 234,137 (355)

Dual‐Action 3D Bioprinted Scaffolds with MXene Quantum Dots for Tumor Suppression and Breast Tissue Regeneration Postmastectomy

Advanced NanoBiomed Research, EarlyView.
Four types of 3D hydrogel scaffolds—acellular, acellular with MXene quantum dots (MQDs), cellular, and cellular with MQDs—are developed for postmastectomy breast cancer therapy. Among them, the acellular MQD scaffold uniquely prevents tumor recurrence while promoting tissue regeneration, offering a dual‐function platform that may reduce reliance on ...
Damla Alkaya, Ozge Ozgenc, Ahmet Ceylan, Okan Ekim, Gamze Aykut, Leena Regi Saleth, Mehmet Altay Unal, Sadettin Er, Mesut Tez, Sanjiv Dhingra, Açelya Yilmazer   +10 more
wiley   +1 more source

Triggering of β1-Integrin Chain Induces Platelet Adhesion to Cultured Endothelium [PDF]

, 1997
Aldo Del Maschio, Inés Martín-Padura, Sergio Bernasconi, Elisabetta Dejana   +3 more
openalex   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source

Induction of Cell Scattering by Expression of β1 Integrins in β1-Deficient Epithelial Cells Requires Activation of Members of the Rho Family of Gtpases and Downregulation of Cadherin and Catenin Function

, 1999
Clotilde Gimond, Arjan van der Flier, Sanne van Delft, Cord Brakebusch, Ingrid Kuikman, John G. Collard, Reinhard Fässler, Arnoud Sonnenberg   +7 more
openalex   +1 more source

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

Advanced NanoBiomed Research, EarlyView.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou, Tianyi Xia, Jiheng Xiao, Jianhui Xiang, Hanhong Fang, Haoran Zhou, Yiqiang Hu, Liming Xiong   +7 more
wiley   +1 more source

Vav2 Activates Rac1, Cdc42, and RhoA Downstream from Growth Factor Receptors but Not β1 Integrins [PDF]

, 2000
Betty P. Liu, Keith Burridge
openalex   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Cutting Edge: A Novel Function for the SLAP-130/FYB Adapter Protein in β1 Integrin Signaling and T Lymphocyte Migration [PDF]

, 2000
Anne Hunter, Nadine Ottoson, Nancy J. Boerth, Gary A. Koretzky, Yoji Shimizu   +4 more
openalex   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Chemokines Fail to Up-Regulate β1 Integrin-Dependent Adhesion in Human Th2 T Lymphocytes [PDF]

, 2000
Barbara Clissi, Daniele D’Ambrosio, Jens Geginat, Lucia Colantonio, Alexandre Morrot, Norman W. Freshney, Julian Downward, Francesco Sinigaglia, Ruggero Pardi   +8 more
openalex   +1 more source