Results 211 to 220 of about 145,582 (257)

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

DIRAS3 Inhibits Ovarian Cancer Cell Growth by Blocking the Fibronectin-Mediated Integrin β1/FAK/AKT Signaling Pathway. [PDF]

Cells
Guo J, Santiago-O'Farrill JM, Orellana V, Ozyurt R, Yang H, Pina M, Bildik G, Mao W, Bast RC, Lu Z.   +9 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

TNS4 promotes lymph node metastasis of gastric cancer by interacting with integrin Β1 and inducing the activation of fibroblastic reticular cell. [PDF]

Cancer Cell Int
Zhang X, Su GH, Bao TS, He WP, Wang YY, Zhou YQ, Xie JX, Wang F, Lu R, Zhang S, Yi SQ, Li Q, Jiang SH, Li H, Hu LP, Li J, Xu J.   +16 more
europepmc   +1 more source

Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance

Periodontology 2000, EarlyView.
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf, Ulrike Schulze‐Späte, Thomas Van Dyke, Stefan Wolfart, Thomas Dietrich, Alberto Ortiz, Zhuojun Wu, Joachim Jankowski   +7 more
wiley   +1 more source

Fast-Relaxing Hydrogels Promote Pancreatic Adenocarcinoma Cell Aggressiveness through Integrin β1 Signaling. [PDF]

Biomacromolecules
Nguyen H, Luong NH, Peil JK, Tong Y, Mitchell DK, Fishel ML, Lin CC.   +6 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Correction: An et al. Integrin β1-Mediated Cell-Cell Adhesion Augments Metformin-Induced Anoikis. <i>Int. J. Mol. Sci.</i> 2019, <i>20</i>, 1161. [PDF]

Int J Mol Sci
An T, Zhang Z, Li Y, Yi J, Zhang W, Chen D, Ao J, Xiao ZX, Yi Y.   +8 more
europepmc   +1 more source

Shared molecular framework and bidirectional effects of osteoporosis on periodontal disease and dental implant therapy in the elderly

Periodontology 2000, EarlyView.
Abstract Objectives This review synthesizes evidence regarding the prevalence, epidemiological associations, and mechanistic pathways between osteoporosis, periodontal disease, and dental implant therapy. Materials and Methods A literature review was conducted to identify studies focused on: osteoporosis, periodontal disease, and dental implants ...
Samin Sirous, Jaclyn C. Chalmers, Pin‐Ying Li, Yumna Subhani, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source