Results 231 to 240 of about 234,137 (355)

ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK. [PDF]

J Exp Clin Cancer Res, 2023
Cui L, Lu Y, Zheng J, Guo B, Zhao X.
europepmc   +1 more source

Apically Exposed, Tight Junction-Associated β1-Integrins Allow Binding and YopE-Mediated Perturbation of Epithelial Barriers by Wild-Type Yersinia Bacteria [PDF]

, 2000
Farideh Tafazoli, Anna Holmström, Åke Forsberg, Karl‐Eric Magnusson   +3 more
openalex   +1 more source

Building Immunocompetent Cerebral Organoids From a Developmental Perspective

Glia, EarlyView.
Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statistical analysis to help develop standardized protocols. ABSTRACT Cerebral organoids derived from human induced pluripotent stem cells (iPSCs) are increasingly ...
Xabier Cuesta‐Puente, Marco Gonzalez‐Dominguez, Marta Pereira‐Iglesias, Nerea Perez‐Arriazu, Patricia Villegas‐Zafra, Paula Ramos‐Gonzalez, Fabio Cavaliere, Nora Bengoa‐Vergniory, Amanda Sierra   +8 more
wiley   +1 more source

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells. [PDF]

Nat Cell Biol
Conway JRW, Joshi O, Kaivola J, Follain G, Gounis M, Kühl D, Ivaska J.   +6 more
europepmc   +1 more source

FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation. [PDF]

J Mammary Gland Biol Neoplasia, 2023
Mieczkowski K, Popeda M, Lesniak D, Sadej R, Kitowska K.   +4 more
europepmc   +1 more source

There Is Temporal and Spatial Expression of α1 (IV), α2 (IV), α5 (IV), α6 (IV) Collagen Chains and β1 Integrins During the Development of the Basal Lamina in an “In Vitro” Skin Model

, 1997
Raúl Fleischmajer, Klaus Kühn, Yoshikazu Sato, Ewan MacDonald, Jerome S. Perlish, Te‐Cheng Pan, M. L. Chu, Yumiko Kishiro, Toshitaka Oohashi, Suzanne M. Bernier, Yoshi Yamada, Yoshifumi Ninomiya   +11 more
openalex   +1 more source

Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage

Glia, EarlyView.
NBCe1 is upregulated in reactive astrocytes following ischemic stroke. Deletion of astrocytic Nbce1 reduces stroke volume, preserves AQP4 polarization, reduces BBB permeability, and improves neurological function after ischemic stroke. ABSTRACT The electrogenic sodium bicarbonate transporter 1 (NBCe1/Slc4a4), predominantly expressed in astrocytes, is ...
Okan Capuk, Elise Berthold, Kathiravan Kaliyappan, Mansi Avunoori, Rajesh Muduganti, Sanjana Krishna, Shamseldin Metwally, Mary McFarland, Shanshan Song, Victoria Fiesler, Sydney Fischer, Lesley M. Foley, T. Kevin Hitchens, Susannah Waxman, Ian A. Sigal, Shefeeq M. Theparambil, Gulnaz Begum   +16 more
wiley   +1 more source

Retraction: Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Importance of the tubulointerstitium in human glomerulonephritis. II. Distribution of integrin chains β1, α1 to 6 and αV

, 1997
Prabir Roy‐Chaudhury, Graham S. Hillis, Stuart Mcdonald, John G. Simpson, David A. Power   +4 more
openalex   +1 more source

Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin

International Journal of Cancer, EarlyView.
What's New? Integrins are critical mediators of cell adhesion and migration and have been implicated in cancer progression. Here, the authors show that endothelial cells in target organs of colorectal cancer metastasis express fibronectin, and that colorectal cancer tumour cells can bind fibronectin through integrin β6. This interaction is resistant to
Chiara Van Passen, Julia Krug, Luisa Weiß, Mariam Mohamed Abdou, Philipp Tripal, Benjamin Schmid, René Krüger, Yanmin Lyu, Bisan Abdalfatah Zohud, Katja Petter, Carol Geppert, Susanne Merkel, Barbara Bärthlein, Philipp Busenhart, Michael Scharl, Elisabeth Naschberger, Michael Stürzl   +16 more
wiley   +1 more source