Results 241 to 250 of about 86,429 (265)

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Biomaterial Surface-Mediated Macrophages Exert Immunomodulatory Roles by Exosomal CCL2-Induced Membrane Integrin β1 Trafficking in Recipient Cells. [PDF]

Adv Sci (Weinh)
Zhao Y, Hang R, Li H, Sun Y, Yao R, Huang X, Zhang X, Yao X, Wang H, Xiao Y, Huang D, Han Y, Wang X, Hang R.   +13 more
europepmc   +1 more source

Regulating Integrin β1 to Restore Gonadotropin-Releasing Hormone-Tanycyte Unit Function in Polycystic Ovary Syndrome-Related Hypothalamic Dysregulation. [PDF]

Research (Wash D C)
Wang Y, Tong X, Xiao Y, Wang Y, Hu W, Lu W, Chen Y, Li J, Gao W, Gao H, Tian Y, Dai S, Feng Y.   +12 more
europepmc   +1 more source

Adhesion of rat glomerular epithelial cells to extracellular matrices: Role of β1 integrins

, 1992
Andrey V. Cybulsky, Salvatore Carbonetto, Qingli Huang, Alison J. McTavish, M. D. Cyr   +4 more
openalex   +1 more source

Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localization. [PDF]

Commun Biol
Wang G, Peng T, Chen L, Xiong K, Ju L, Qian K, Zhang Y, Xiao Y, Wang X.   +8 more
europepmc   +1 more source

β3 Integrin Promotes TGF-β1/H2O2/HOCl-Mediated Induction of Metastatic Phenotype of Hepatocellular Carcinoma Cells by Enhancing TGF-β1 Signaling

, 2013
Xinxia Feng, Mei Liu, Wei Yan, Zhenzhen Zhou, Yujia Xia, Wei Tu, Peiyuan Li, Dean Tian   +7 more
openalex   +2 more sources

Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease. [PDF]

Nat Commun
Elwakiel A, Gupta D, Rana R, Manoharan J, Al-Dabet MM, Ambreen S, Fatima S, Zimmermann S, Mathew A, Li Z, Singh K, Gupta A, Pal S, Sulaj A, Kopf S, Schwab C, Baber R, Geffers R, Götze T, Alo B, Lamers C, Kluge P, Kuenze G, Kohli S, Renné T, Shahzad K, Isermann B.   +26 more
europepmc   +1 more source

The role of Notch and Integrin-β1 signaling in muscle development

, 2014
Maciej T. Czajkowski
openalex   +2 more sources

Correction: Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.

Elife
Zhang Y, Sun L, Li H, Ai L, Ma Q, Qiao X, Yang J, Zhang H, Ou X, Wang Y, Chen G, Xue J, Zhu X, Zhao Y, Yang Y, Liu C.   +15 more
europepmc   +1 more source

Enhanced Tumor-Targeted Delivery of Arginine-Rich Peptides via a Positive Feedback Loop Orchestrated by Piezo1/integrin β1 Signaling Axis. [PDF]

Adv Sci (Weinh)
Ma M, Li X, Jing M, Zhang P, Zhang M, Wang L, Liang X, Jiang Y, Li J, He J, Wang X, Lin M, Wang L, Fan J.   +13 more
europepmc   +1 more source