Results 241 to 250 of about 210,881 (328)
Immune complex-stimulated neutrophil LTB4 production is dependent on beta 2 integrins. [PDF]
Irene Graham+3 more
openalex +1 more source
Swimming induces bone loss via regulating mechanical sensing pathways in bone marrow. [PDF]
Fu S, Lu Y, Sun W, Chen W, Lin C, Qin A.
europepmc +1 more source
High QSOX2 enhances stemness, drug resistance, and metastasis of ESCC cells. QSOX2‐mediated disulfide bond modification activates mTOR/c‐Myc signaling. CAFs‐secreted IGF‐1 drives mTOR/c‐Myc/QSOX2 positive feedback loop. Combining Ebselen, rapamycin, and cisplatin induces tumor dormancy in mice.
Wo‐Ming Chen+12 more
wiley +1 more source
Mechanosignaling via Integrins: Pivotal Players in Liver Fibrosis Progression and Therapy. [PDF]
Sharip A, Kunz J.
europepmc +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim+12 more
wiley +1 more source
Environmental Toxicants and Their Disruption of Integrin Signaling in Lipid Rafts. [PDF]
Izard T.
europepmc +1 more source
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang+11 more
wiley +1 more source