Results 361 to 370 of about 299,855 (390)
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Integrin-linked kinase: integrin’s mysterious partner
Current Opinion in Cell Biology, 2004Integrin-mediated cell adhesion regulates a vast number of biological processes including migration, survival and proliferation of cells. It is therefore not surprising that defects in integrin function are often rate-limiting for development and profoundly affect the progression of several diseases.
Reinhard Fässler +4 more
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Thrombosis and Haemostasis, 2001
SummaryIntegrins are cell surface adhesion receptors that participate in a variety of important processes throughout the vasculature. Here we summarize some recent findings on the regulation of integrin mediated cellular adhesion. Particular emphasis is placed on the regulation of integrin affinity for ligand (activation), although this is just one ...
D G, Woodside, S, Liu, M H, Ginsberg
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SummaryIntegrins are cell surface adhesion receptors that participate in a variety of important processes throughout the vasculature. Here we summarize some recent findings on the regulation of integrin mediated cellular adhesion. Particular emphasis is placed on the regulation of integrin affinity for ligand (activation), although this is just one ...
D G, Woodside, S, Liu, M H, Ginsberg
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Purification of integrins and characterization of integrin-associated proteins
2002Publisher Summary This chapter discusses the purification protocols of integrin and focuses on the details of the procedure that allows identification of the integrin-associated proteins through the production of the monoclonal antibodies (mAbs). General biochemical protocols are applied to purify integrins.
Fedor Berditchevski, Johannes A. Eble
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1993
Integrins are expressed on almost every cell type and are responsible for the linkage of the extracellular matrix with the cytoskeleton. In this review I have focused on the intra- and extracellular proteins that bind to integrins. Although many integrins bind to the same extracellular ligand, they mostly recognize different sites on these ligands ...
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Integrins are expressed on almost every cell type and are responsible for the linkage of the extracellular matrix with the cytoskeleton. In this review I have focused on the intra- and extracellular proteins that bind to integrins. Although many integrins bind to the same extracellular ligand, they mostly recognize different sites on these ligands ...
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Integrins: Versatility, modulation, and signaling in cell adhesion
Cell, 1992R. Hynes
semanticscholar +1 more source
Cell Differentiation and Development, 1990
We have undertaken the study of integrins specifically or predominantly expressed in epithelial cells, as they may be involved in establishing and maintaining properties peculiar to epithelia, such as polarization and morphogenetic movements. We describe here recent results regarding two such integrins.
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We have undertaken the study of integrins specifically or predominantly expressed in epithelial cells, as they may be involved in establishing and maintaining properties peculiar to epithelia, such as polarization and morphogenetic movements. We describe here recent results regarding two such integrins.
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Matrix Biology, 1997
Integrins provide dynamic links between cells and extracellular matrix molecules. Although integrins were originally viewed as relatively simple adhesion molecules, it soon became clear that intracellular signal transduction initiated by integrins is centrally involved in many cellular processes.
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Integrins provide dynamic links between cells and extracellular matrix molecules. Although integrins were originally viewed as relatively simple adhesion molecules, it soon became clear that intracellular signal transduction initiated by integrins is centrally involved in many cellular processes.
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BioEssays, 1996
AbstractThe integrin family was originally described as a family of adhesion receptors, utilized by cells for attachment to and migration across components of the extracellular matrix. Epithelial cells in adult tissues are generally stationary cells, but these cells nevertheless express several different integrins. This review will discuss the evidence
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AbstractThe integrin family was originally described as a family of adhesion receptors, utilized by cells for attachment to and migration across components of the extracellular matrix. Epithelial cells in adult tissues are generally stationary cells, but these cells nevertheless express several different integrins. This review will discuss the evidence
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Integrins and other cell adhesion molecules
The FASEB Journal, 1990S. Albelda, C. Buck
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