Results 1 to 10 of about 24,855 (253)

The Link between Occurrence of Class I Integron and Acquired Aminoglycoside Resistance in Clinical MRSA Isolates

Antibiotics, 2021
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infections because of its high resistance. Here, we study the antibiotic resistance in MRSA clinical isolates and their relation to integron I occurrence.
Ahmed M. El-Baz, Galal Yahya, Basem Mansour, Mohamed M. A. El-Sokkary, Reem Alshaman, Abdullah Alattar, Amira M. El-Ganiny   +6 more
doaj   +2 more sources

A comprehensive survey of integron-associated genes present in metagenomes

BMC Genomics, 2020
Background Integrons are genomic elements that mediate horizontal gene transfer by inserting and removing genetic material using site-specific recombination.
Mariana Buongermino Pereira, Tobias Österlund, K Martin Eriksson, Thomas Backhaus, Marina Axelson-Fisk, Erik Kristiansson   +5 more
doaj   +2 more sources

Prevalence of integron classes in Gram-negative clinical isolated bacteria in Iran: a systematic review and meta-analysis [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Integrons, as a potential element in the distribution and maintenance of drug resistance, have thoroughly been established. It is known that the high prevalence of integrons in multidrug-resistant (MDR) clinical isolates has become a ...
Ali Pormohammad, Ramin Pouriran, Hadi Azimi, Mehdi Goudarzi   +3 more
doaj   +2 more sources

Distinct ARG profiles associated with class 1 integrons in municipal and industrial wastewater treatment plants [PDF]

Environmental Science and Ecotechnology
Class 1 integrons facilitate horizontal gene transfer, significantly influencing antibiotic resistance gene (ARG) dissemination within microbial communities.
Yan Zhang, Zhiguo Su, Xuyang Qiu, He Liu, Donghui Wen, Lyujun Chen   +5 more
doaj   +2 more sources

Transmissible ST3-IncHI2 Plasmids Are Predominant Carriers of Diverse Complex IS26-Class 1 Integron Arrangements in Multidrug-Resistant Salmonella

Frontiers in Microbiology, 2018
Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria.
Hang Zhao, Wenyao Chen, Xuebin Xu, Xiujuan Zhou, Chunlei Shi   +4 more
doaj   +2 more sources

Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance

mBio, 2017
Integrons ensure a rapid and “on demand” response to environmental stresses driving bacterial adaptation. They are able to capture, store, and reorder functional gene cassettes due to site-specific recombination catalyzed by their integrase.
Céline Loot, Aleksandra Nivina, Jean Cury, José Antonio Escudero, Magaly Ducos-Galand, David Bikard, Eduardo P. C. Rocha, Didier Mazel   +7 more
doaj   +2 more sources

Profile and resistance levels of 136 integron resistance genes

npj antimicrobials and resistance, 2023
Integrons have played a major role in the rise and spread of multidrug resistance in Gram-negative pathogens and are nowadays commonplace among clinical isolates.
Alberto Hipólito, Lucía García-Pastor, Ester Vergara, Thomas Jové, J. Escudero   +4 more
semanticscholar   +1 more source

Integron Functionality and Genome Innovation: An Update on the Subtle and Smart Strategy of Integrase and Gene Cassette Expression Regulation

Microorganisms, 2022
Integrons are considered hot spots for bacterial evolution, since these platforms allow one-step genomic innovation by capturing and expressing genes that provide advantageous novelties, such as antibiotic resistance.
E. Fonseca, A. Vicente
semanticscholar   +1 more source

High frequency of multidrug-resistant (MDR) Klebsiella pneumoniae harboring several β-lactamase and integron genes collected from several hospitals in the north of Iran

Annals of Clinical Microbiology and Antimicrobials, 2021
Background Klebsiella pneumoniae is one of the leading causes of hospital outbreaks worldwide. Also, antibiotic-resistant K. pneumoniae is progressively being involved in invasive infections with high morbidity and mortality. The aim of the current study
Mojgan Farhadi, M. Ahanjan, H. Goli, M. Haghshenas, M. Gholami   +4 more
semanticscholar   +1 more source

The linkage between prevalence of integron I and reduced susceptibility to biocides in MDR Klebsiella pneumoniae isolated from neonates

Iranian Journal of Microbiology, 2023
Background and Objectives: Klebsiella pneumoniae causes challenging nosocomial fatal infections including neonatal sepsis. Our study aims at clarifying the contribution of integrons in the observed reduced susceptibility of multidrug-resistant (MDR) K ...
Pola Samir, Ahmed Mohamed El-Baz, Hany Ibrahim Kenawy   +2 more
doaj   +1 more source