Results 61 to 70 of about 328,626 (335)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Accretion disk coronae of Intermediate Polar Cataclysmic Variables - 3D MagnetoHydro-Dynamic modeling and thermal X-ray emission [PDF]

, 2017
IPCVs contain a magnetic, rotating white dwarf surrounded by a magnetically truncated accretion disk. To explain their strong flickering X-ray emission, accretion has been successfully taken into account. Nevertheless, observations suggest that accretion
Barbera, Enrico, Orlando, Salvatore, Peres, Giovanni   +2 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Latent Heat Flux and Turbulent Kinetic Energy Measurements by Lidar in the Frame of the WaLiNeAs Campaign

Remote Sensing
In the present work, we report daytime latent heat flux profile measurements in the convective boundary layer (CBL) obtained from the combined use of a wind lidar and a thermodynamic Raman lidar.
Paolo Di Girolamo, Donato Summa, Ilaria Gandolfi, Marco Di Paolantonio, Marco Rosoldi, Benedetto De Rosa, Davide Dionisi, Cyrille Flamant, Giuseppe D’Amico   +8 more
doaj   +1 more source

Heating and cooling of magnetars with accreted envelopes

, 2009
We study the thermal structure and evolution of magnetars as cooling neutron stars with a phenomenological heat source in an internal layer. We focus on the effect of magnetized (B > 10^{14} G) non-accreted and accreted outermost envelopes composed of ...
A. D. Kaminker, A. Y. Potekhin, Aguilera, Aguilera, Aguilera, Akmal, Alpar, Beloborodov, Bildsten, Chang, Chatterjee, Chevalier, Chevalier, Chugunov, Colpi, D. G. Yakovlev, Durant, Ertan, G. Chabrier, Geppert, Geppert, Ginzburg, Gnedin, Gudmundsson, Gusakov, Haensel, Ho, Kaminker, Kaminker, Kaminker, Kulkarni, Lattimer, Lyutikov, Mereghetti, Mereghetti, Morii, Morley, Muno, Nelson, Pavlov, Pons, Pons, Potekhin, Potekhin, Potekhin, Potekhin, Pérez-Azorín, Rea, Rea, Rho, Romanova, Shibanov, Slane, Tam, Thompson, Thompson, Tiengo, van Kerkwijk, Van Riper, Vancura, Vasisht, Ventura, Walter, Wang, Woods, Woods, Woods, Yakovlev, Yakovlev, Yakovlev   +69 more
core   +1 more source

Deduction of temperature fluctuations in transient compression wind tunnels using incompressible turbulent flow data [PDF]

, 2009
Wind tunnels and other aero-thermal experimental facilities are likely to make a contribution to the optimisation of energy and propulsion systems for the foreseeable future.
Buttsworth, D. R., Widodo, A.
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Intense summer heat fluxes in artificial turf harm people and environment

Landscape and Urban Planning, 2017
Abstract Artificial turf (AT) sports fields have increasingly replaced natural turf (NT). High AT material-cum-air temperature incurs heat-stress impacts on athletes, demanding better understanding of thermal regimes vis-a-vis weather conditions. Adjacent AT and NT sites in humid-tropical Hong Kong were studied. Four radiant-energy components (direct-
openaire   +3 more sources

Effects of surface heat flux‐induced sea surface temperature changes on tropical cyclone intensity [PDF]

Geophysical Research Letters, 2003
It is known that in deep and open oceans, the effect of sea surface sensible and evaporative heat fluxes on the tropical cyclone‐induced sea surface cooling is small compared to that caused by turbulent mixing and cold water entrainment into the upper ocean mixed‐layer.
Shen, Weixing, Ginis, Isaac
openaire   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source