Results 41 to 50 of about 4,442,613 (109)

Improvements on the planning and delivery of intensity-modulated arc therapy [PDF]

, 2010
In the past decade, intensity-modulated radiation therapy (IMRT) has taken a significant step towards dose conformality and has now become a standard radiotherapy technique in the clinic.
Tang, G.
core  

Application of constant vs. variable relative biological effectiveness in treatment planning of intensity-modulated proton therapy

, 2011
To investigate in a simulation study whether using a variable relative biological effectiveness (RBE) in calculation and optimization of intensity-modulated proton therapy (IMPT) instead of using an RBE of 1.1 would result in significant changes in the ...
Huber, Peter E, Jensen, Alexandra D, Oelfke, Uwe, Frese, Malte C, Taheri-Kadkhoda, Zahra,, Wilkens, Jan J   +5 more
core   +1 more source

Dental management in head and neck cancers: from intensity-modulated radiotherapy with photons to proton therapy

, 2022
International audienceIntroduction: Despite reduction of xerostomia with intensity-modulated compared to conformal X-ray radiotherapy, radiation-induced dental complications continue to occur.
Moignier, Cyril, Dutheil, Pauline, Drouet, Julien, Thariat, Juliette, Beddok, Arnaud, Parvathaneni, Upendra, Marcy, Pierre-Yves, Dore, Melanie, Epstein, Joel, Falek, Sabah, Vela, Anthony, Regmi, Rajesh, Herault, Joel, Letwin, Noah E., Anthony Vela, Julien Drouet, Pauline Dutheil, Cyril Moignier, Noah E. Letwin, Joel Herault, Melanie Dore, Juliette Thariat, Pierre-Yves Marcy, Joel Epstein, Arnaud Beddok, Upendra Parvathaneni, Sabah Falek, Rajesh Regmi   +27 more
core   +3 more sources

Single high‐energy arc proton therapy with Bragg peak boost (SHARP)

Journal of Medical Radiation Sciences
Introduction Because of the co‐location of critical organs at risk, base of skull tumours require steep dose gradients to achieve the prescribed dosimetric criteria.
Scott N. Penfold, Alexandre M. C. Santos, Melanie Penfold, Emma Shierlaw, Rosanna Crain   +4 more
doaj   +1 more source

Evaluation of Robustness to Setup and Range Uncertainties for Head and Neck Patients Treated With Pencil Beam Scanning Proton Therapy. [PDF]

, 2016
PURPOSE To evaluate the robustness of head and neck plans for treatment with intensity modulated proton therapy to range and setup errors, and to establish robustness parameters for the planning of future head and neck treatments.
Lomax, Antony J, Weber, Damien Charles, Malyapa, Robert, Albertini, Francesca, Lowe, Matthew, Bolsi, Alessandra, Malyapa, Robert (author), Weber DC, Albertini, Francesca (author), Lomax, Antony J. (author), Bolsi, A, Albertini, F, Bolsi, Alessandra (author), Malyapa R, Albertini F, Lowe, Matthew (author), Lomax AJ, Weber, D, Lomax, A, Weber, Damien C. (author), Lowe M, Bolsi A, Malyapa, R   +22 more
core   +1 more source

Physician- and Patient-Reported Outcomes Following Contemporary Image Guided Intensity Modulated Proton Therapy for Prostate Cancer: Results From the Prospective PRO-Cube Study

Advances in Radiation Oncology
Purpose: Multiple prospective studies have established the safety of proton therapy for localized prostate cancer. However, prospective data defining physician-reported adverse events (AEs) and patient-reported outcomes (PROs) with contemporary image ...
Sham Sundar, MD, Srinivas Chilukuri, MD, Manikandan Arjunan, MSc, PhD, Ramakrishna Kamath, MD, Abhilasha Sinha, MD, Mahalakshmi Palani, BSc, Pankaj Kumar Panda, MSc, Sujith K. Mullapally, DM, Srivathsan Ramani, MCh, Narasimhan Ragavan, MCh, Prashant Jawahar, MD, Jaykanth Amalachandran, MD, Dayananda Shamurailatpam Sharma, MSc, PhD, Rakesh Jalali, MD   +13 more
doaj   +1 more source

Clinical implementation of intensity modulated proton therapy for testicular seminoma

Acta Oncologica
Background and purpose: We have previously shown that proton therapy results in considerable reduced doses to abdominal organs at risk (OAR) which likely reduces the patient’s risk of a second malignant tumor, which is vital for this young population ...
Heidi S. Rønde, Jesper F. Kallehauge, Morten Høyer, Anne Birgitte Als, Mads Agerbæk, Jakob Lauritsen, Peter M. Petersen, Lars Dysager, Camilla J.S. Kronborg   +8 more
doaj   +1 more source

New frontiers in proton therapy: applications in cancers

Cancer Communications, 2019
Proton therapy offers dominant advantages over photon therapy due to the unique depth-dose characteristics of proton, which can cause a dramatic reduction in normal tissue doses both distal and proximal to the tumor target volume.
Tai-Ze Yuan, Ze-Jiang Zhan, Chao-Nan Qian   +2 more
doaj   +1 more source

High-dose Intensity-modulated proton therapy versus Standard-dose Intensity-modulated RadIation therapy for esophageal squamous cell carcinoma (HI-SIRI): study protocol for a randomized controlled clinical trial

Trials, 2022
Background Chemoradiotherapy is the standard of care for esophageal cancer as a neoadjuvant treatment before surgery, or as a definitive treatment for unresectable disease.
Chawalit Lertbutsayanukul, Sarin Kitpanit, Danita Kannarunimit, Chakkapong Chakkabat, Sornjarod Oonsiri, Kullathorn Thephamongkhol, Putipun Puataweepong, Kanyarat Katanyoo, Jirasak Sukhaboon, Chokaew Tovanabut, Sirikanya Chongsathientham, Pornravee Treeratsapanich, Jirarat Soonthornrak, Anussara Prayongrat   +13 more
doaj   +1 more source

Dramatic Response of a Large Sacral Chordoma to Intensity Modulated Proton Beam Therapy

, 2017
Sacral chordomas are slow-growing, indolent, and locally invasive tumors that typically present with pain and neurologic dysfunction. Wide en-bloc surgical excision is the primary treatment, but achieving adequate margins is difficult and surgery is ...
Craig Schneider, Schneider, Craig, Morse, Emily, Snider, James W, Emily Morse, Katarina Steacy, Malyapa, Robert, Robert Malyapa, Tejan Diwanji, James W Snider, Steacy, Katarina, Sina Mossahebi, Melissa Vyfhuis, Vyfhuis, Melissa, Mossahebi, Sina, Diwanji, Tejan   +15 more
core   +1 more source