Results 111 to 120 of about 3,925,241 (306)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Efficacy and safety of high-intensity electromagnetic stimulation in the prevention of recurrence of rectocele after surgical treatment

Клинический разбор в общей медицине
The etiology of rectocele is diverse and can be caused by gynaecological and extragenital diseases, but the exact mechanisms of formation of anatomical, functional defects of the pelvic floor and methods of effective treatment from the position of ...
Mekan R. Orazov, Viktor E. Radzinsky, Elena S. Silantieva , Farida F. Minnullina, Roman E. Orekhov, Anastasia E. Pavlova   +5 more
doaj   +1 more source

A decade of winter supraglacial lake drainage across Northeast Greenland using C-band SAR [PDF]

The Cryosphere
This study presents a comprehensive, multi-year assessment of winter supraglacial lake drainages on the Northeast Greenland Ice Sheet, detailing cascading drainage events, in which drainage of one lake triggers a chain of subsequent drainages that often ...
C. W. Dean, R. Scharien, I. Willis, K. A. McDougall   +3 more
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Contrast-Enhanced Ultrasound to Assess Kidney Quality During Ex Situ Normothermic Machine Perfusion

Transplant International
Normothermic machine perfusion (NMP) provides opportunity for viability assessment of donated kidneys. Diminished microvascular perfusion, despite adequate total blood flow, is a key pathophysiology in ischaemia-mediated acute kidney injury.
Samuel J. Tingle, Samuel J. Tingle, Samuel J. Tingle, Chloe Connelly, Emily K. Glover, Emily K. Glover, Emily K. Glover, Ben Stenberg, Andrew McNeill, Georgios Kourounis, Georgios Kourounis, Georgios Kourounis, Beth G. Gibson, Balaji Mahendran, Balaji Mahendran, Balaji Mahendran, Lucy Bates, Lucy Bates, Madison N. Cooper, Madison N. Cooper, Rhys R. Pook, Rhys R. Pook, Samantha Lee, Samantha Lee, Marnie L. Brown, Marnie L. Brown, Rodrigo Figueiredo, Kevin J. Marchbank, Kevin J. Marchbank, Simi Ali, Simi Ali, Neil S. Sheerin, Neil S. Sheerin, Neil S. Sheerin, Colin H. Wilson, Colin H. Wilson, Colin H. Wilson, Emily R. Thompson, Emily R. Thompson, Emily R. Thompson   +39 more
doaj   +1 more source

Deep learning and predictive modelling for generating normalised muscle function parameters from signal images of mandibular electromyography

Medical and Biological Engineering and Computing
Challenges arise in accessing archived signal outputs due to proprietary software limitations. There is a notable lack of exploration in open-source mandibular EMG signal conversion for continuous access and analysis, hindering tasks such as pattern ...
T. Farook, Tashreque Mohammed Haq, Lameesa Ramees, James Dudley   +3 more
semanticscholar   +1 more source

Normalisation of Myosin II channel.

Images of the Myosin II channel from movies prior to (A-D) and after (A’-D’) normalisation, for example, wild-type (200910_3) (A-B’) and twist (201119_1) (C-D’) movies.
Bénédicte Sanson (823497), Claire M. Lye (18462596), Jenny Evans (627426), Alexander Nestor-Bergmann (8086760), Guy B. Blanchard (8086766)   +4 more
core   +1 more source

Yet Another Normalisation Proof for Martin-Lof's Logical Framework - Terms with correct arities are strongly normalising [PDF]

, 2005
In this paper, we prove the strong normalisation for Martin- Lof's Logical Framework, and suggest that ''correct arity'', a condition weaker than well-typedness, will also guarantee the strong ...
Luo, Yong
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Profiling autofluorescence signatures of microplastics from commercial plastic products by flow cytometry and multivariate analysis

Frontiers in Environmental Science
Microplastics exhibit autofluorescence, yet how this optical property varies among particles derived from commercial plastic products and its potential for stain-free differentiation remain poorly understood.
Georgina H. Tilly-Scholes, Connor McIvor, Iliana Delcheva, Iliana Delcheva, Hayden L. Gillings, Hayden L. Gillings, Hayden L. Gillings, Melanie MacGregor, Melanie MacGregor, James S. Paterson, James S. Paterson, James G. Mitchell, James G. Mitchell, Oliver G. Best   +13 more
doaj   +1 more source