Results 111 to 120 of about 3,274,658 (352)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Kemampuan Membedakan Kalimat Fakta Dan Opini Melalui Kegiatan Membaca Intensif Siswa Kelas X SMK-SMAK Padang [PDF]
, 2013 The purpose of this study were to (1) describe the ability of students to determine the sentence facts through intensive reading class X-SMAK SMK Padang, (2) describe the ability of students to determine the sentence opinions through intensive reading ...
Arief, E. (Ermawati) +2 more
core
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Penerapan Strategi Sq3r untuk Meningkatkan Keterampilan Membaca Intensif Siswa Kelas IV Sekolah Dasar [PDF]
, 2013 Penelitian dalam upaya meningkatkan keterampilan membaca intensif pada siswa kelas IV SDN Sekargadung II Pungging Mojokerto dilatarbelakangi oleh rendahnya keterampilan siswa dalam membaca intensif.
YULIANI, N. (NOFIYA)
core +1 more source
Intensive Summer Intervention Drives Linear Growth of Reading Skill in Struggling Readers
Frontiers in Psychology, 2019 A major achievement of reading research has been the development of effective intervention programs for struggling readers. Most intervention studies employ a pre-post design, to examine efficacy, but this precludes the study of growth curves over the ...
Patrick M. Donnelly +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Penggunaan Metode Stad Dengan Media Artikel Berita Sebagai Upaya Peningkatan Keterampilan Membaca Intensif Siswa Kelas VIII E SMP Negeri 1 Kebonagung Tahun 2012/20131 [PDF]
, 2014 Based on the test results and exercises for the students of class VIII E , find the main idea skills through intensive reading students held low . Students do not understand the process and how to read that well , to be able to find the main idea through
Santosa, E. B. (Edy)
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Consciousness as Inner Sensation: Crusius and Kant [PDF]
, 2018 What is it that makes a mental state conscious? Recent commentators have proposed that for Kant, consciousness results from differentiation: A mental state is conscious insofar as it is distinguished, by means of our conceptual capacities, from other ...
Indregard, Jonas Jervell
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source