Results 131 to 140 of about 119,276 (254)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

To Integrate Extensive and Intensive Reading for Middle School Students

open access: yes, 2017
석사학위를 수여받기 위해 제출된 포트폴리오임. 이 논문은 저자가 원문공개에 동의하지 않은 논문으로, 도서관 내에서만 열람이 가능하며, 인쇄 및 저장은 불가합니다.[Introduction] Purpose: To integrate intensive reading (IR) and extensive reading (ER) Rationale: IR and ER approaches are used for developing reading skills ...
이서진
core  

The Impact of Extrinsic Reward on Learners’ Performance and Motivation in Reading

open access: yesRevue des Sciences Humaines, 2015
This work examines the impact of extrinsic reward, as a motivation strategy, on students’ L2 reading motivation and performance. A total sample of 91 second year LMD students of English as a foreign language, at the Department of Arts and English ...
Imène BILOUK
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Integrating Extensive and Intensive reading approaches through reading a novel, Dead Poets Society

open access: yes, 2019
Introduction -Purpose: Integrating Extensive and Intensive reading approaches through reading a novel, Dead Poets Society. -Rationale 1. Extensive reading helps students not only gain reading proficiency, but also improve the overall language ...
한정희
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Combining Extensive and Intensive Reading approaches for Young Learners

open access: yes, 2014
석사학위를 수여받기 위해 제출된 포트폴리오임;☞ 이 논문은 저자가 원문공개에 동의하지 않은 논문으로, 도서관 내에서만 열람이 가능하며, 인쇄 및 저장은 불가합니다.Parents in Korea regard English Education as a key to success. As a result, Early English Education has been popular among Korean parents (Bahk, 2013).
Park, Sun Ju
core  

PENINGKATAN KEMAMPUAN MEMBACA INTENSIF MELALUI COOPERATIVE LEARNING TIPE STAD KELAS VI SDN 8 PADANG LAWEH

open access: yesJurnal Prima Edukasia, 2015
Tujuan penelitian ini adalah untuk meningkatkan proses pembelajaran dan kemampuan membaca intensif siswa kelas VI SDN 8 Padang Laweh dengan pendekatan kooperatif tipe STAD. Penelitian ini menggunakan desain penelitian tindakan kelas.
Tasrial Efendi, Suhardi Suhardi
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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