Results 121 to 130 of about 3,283,391 (348)

Spark deployment and performance evaluation on the MareNostrum supercomputer [PDF]

, 2015
In this paper we present a framework to enable data-intensive Spark workloads on MareNostrum, a petascale supercomputer designed mainly for compute-intensive applications.
Ayguadé Parra, Eduard, Becerra Fontal, Yolanda, Carrera Pérez, David, Girona Turell, Sergi, Gounaris, Anastasios, Labarta Mancho, Jesús José, Torres Viñals, Jordi, Tous Liesa, Rubén, Tripiana, Carlos, Valero Cortés, Mateo   +9 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Kemampuan Membedakan Kalimat Fakta Dan Opini Melalui Kegiatan Membaca Intensif Siswa Kelas X SMK-SMAK Padang [PDF]

, 2013
The purpose of this study were to (1) describe the ability of students to determine the sentence facts through intensive reading class X-SMAK SMK Padang, (2) describe the ability of students to determine the sentence opinions through intensive reading ...
Arief, E. (Ermawati), Emidar, E. (Emidar), Sartika, R. (Rina)   +2 more
core  

Quality control for multiple breath washout tests in multicentre bronchiectasis studies:Experiences from the BRONCH-UK clinimetrics study [PDF]

, 2018
Multiple Breath Washout (MBW) to measure Lung Clearance Index (LCI) is increasingly being used as a secondary endpoint in multicentre bronchiectasis studies.
Bradbury, Ian, Bradley, Judy M., Carroll, Mary, Chalmers, James, Cosgrove, Denise, DeSoyza, Anthony, Elborn, J. Stuart, Ferguson, Kathryn, Gatheral, Timothy, Hill, Adam T., Hurst, John R., Johnson, Chris, Lakshmipathy, Gokul R., Loebinger, Michael, O'Neill, Katherine   +14 more
core   +3 more sources

Intensive Summer Intervention Drives Linear Growth of Reading Skill in Struggling Readers

Frontiers in Psychology, 2019
A major achievement of reading research has been the development of effective intervention programs for struggling readers. Most intervention studies employ a pre-post design, to examine efficacy, but this precludes the study of growth curves over the ...
Patrick M. Donnelly, Patrick M. Donnelly, Elizabeth Huber, Elizabeth Huber, Jason D. Yeatman, Jason D. Yeatman   +5 more
doaj   +1 more source

Aquisition Activities in English Foreign Language (Efl) Teaching [PDF]

, 2015
This paper aims at discussing the use of four possible ways to conduct acquisition activities in English Foreign Language (EFL) classroom teaching and focuses on some of the appealing uses of vivid linking, story retelling, self directed statement and ...
Bahri, S. (Syamsul), Saragih, F. H. (Farida)   +1 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Extensive reading in a second language : literature review and pedagogical implications [PDF]

, 2015
textThis Report explores the importance of including extensive reading (ER) program in English as a second language (ESL) or English as a foreign language (EFL) context.
Hong, Sunju
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source