Results 81 to 90 of about 108,794 (260)
Al Ibtida: Jurnal Pendidikan Guru MI, 2018 AbstrakBerdasarkan hasil observasi di kelas V SD Negeri Sunyaragi I diketahui bahwa siswa masih mengalami kesulitan dalam memahami suatu bacaan. Salah satu penyebabnya adalah guru cenderung menggunakan metode ceramah dan belum mengoptimalkan kemampuan ...
Patimah Patimah, Faisal Abdullah
doaj +1 more source
, 2023 This article tackles the teaching of intensive reading in the EFL classroom. It reviews the principles that govern intensive reading and how they could be used to teach English to non-native speakers. Reading is one of the four necessary skills that must be developed when learning a foreign language.
openaire +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Bringing Reading to Life. Tips for Vitalizing Reading in Primary School
RATE IssuesThis article explores the way in which reading can be brought to life in the English lessons starting from the roles of the teacher in intensive reading and going on with examples of activities through which we can bring reading to life. The roles of the
Ligia-Daniela Botiza
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
JISAE (Journal of Indonesian Student Assessment and Evaluation)Effective classroom management is a crucial foundation in the success of learning in Primary School (SD), given the unique characteristics of students at this developmental age.
Bambang Afriadi, Fitri Fitri
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