Results 141 to 150 of about 233,101 (310)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
A national benchmarking survey to explore the use of dose error reduction software in adult intensive care units (ICUs). [PDF]
Morgan S, Lamont S.
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Exploring the training, implementation and utilisation experiences of lung ultrasound accredited physiotherapists in the United Kingdom: A national survey. [PDF]
Hayward S +3 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Exploring the capacity of smoking cessation services in the Philippines. [PDF]
Santiago AJA +3 more
europepmc +1 more source
132 Management of Sedation, Analgesia, and Muscle Relaxation in Critically Ill Children: A Survey in Paediatric Intensive Care Units in Spain [PDF]
Santiago Mencía +6 more
openalex +1 more source

