Results 111 to 120 of about 61,615 (213)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Intention to Leave Among Quality Nurses in Public Hospitals in Kuwait: A Sequential Explanatory Mixed-Methods Study. [PDF]

Healthcare (Basel)
ALFadhalah T, Ali S, Lari M, Al Kharji H, Elamir H.   +4 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Work-Family Conflict and Intention to Leave Among Nursing Professionals: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Ventura-Silva JMA, Ribeiro OMPL, Ribeiro MP, Faria ADCA, Barros SCDC, Gasparino RC, Silva CB, Forte ECN, Bozzetti M, Demirsoy N, Zuge SS.   +10 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Exploring the intention to leave the nursing profession: a descriptive qualitative study in Italy. [PDF]

Front Public Health
Saraga M, Quirini S, Peghetti A, Durante S, De Rosa M, Vetromile A, Golfieri L, Turolla A, Benini S.   +8 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Factors Influencing Intention to Leave Among Nurse Managers: A Cross-Sectional Study. [PDF]

Worldviews Evid Based Nurs
Simonetti V, Franconi I, Piermattei N, Faragalli A, Fioretti M, Rossolini D, Santamaria G, Gesuita R, Cicolini G.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Coordinator Leadership in the Relationship Between Burnout and Nurses' Intention to Leave: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Zaghini F, Marti F, Gonzalez CIA, Lo Monaco M, Bartoli D, Figura M, Gioiello G.   +6 more
europepmc   +1 more source