Results 61 to 70 of about 67,618 (299)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Investigating the relationship between job involvement and intention to leave job in anesthetist employed in Sanandaj hospitals in 2018

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: job involvement and intention to leave job are important feedbacks of work. The purpose of this study was to investigate the relationship between job involvement and intention to leave job among anesthetist employed in Sanandaj ...
kamel abdi, Mokhtar Yaghobi, Arvin Barzanji, Shilan Ghaderi, Daem Roushani, Aram Karimian   +5 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The intention to leave among academics in Iran: an examination of their work-life quality and satisfaction

BMC Nursing
Background Despite the importance of faculty retention, there is little understanding of how demographic variables, professional and institutional work-life issues, and satisfaction interact to explain faculty intentions to leave.
Akram Ghahramanian, Farzaneh Bagheriyeh, Parvaneh Aghajari, Mohammad Asghari-Jafarabadi, Pedram Abolfathpour, Azad Rahmani, Amirreza Nabighadim, Alireza Hajieskandar   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Relationship between Cancer and Intention to Leave Work among Older Workers: A Cross-Sectional Internet-Based Study

Medicina
Background and Objectives: Limited research has focused on the relationship between cancer, job loss, and factors associated with job loss among older workers. Therefore, in this study, we aimed to examine the relationship between cancer and intention to
Ryutaro Matsugaki, Shinya Matsuda, Akira Ogami   +2 more
doaj   +1 more source

Predictors of nursing workers’ intention to leave the work unit, health institution and profession

Revista Latino-Americana de Enfermagem, 2019
Objective: to identify the factors related to the nursing workers’ intention to leave the work unit, health institution and profession. Method: cross-sectional study with quantitative approach was carried out with 267 nursing workers from seven ...
Maiara Bordignon, Maria Inês Monteiro
doaj   +3 more sources

A study on the impact of role stress on engineer intention to leave in Indian construction firms

Scientific Reports, 2022
Construction jobs are stressful, and high employee turnover is one of the significant issues affecting the growth and development of construction firms worldwide.
M. Hazeen Fathima, C. Umarani
doaj   +1 more source