Results 91 to 100 of about 265,449 (188)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Head and trunk movement strategies in quiet stance : from the deficit of vestibular loss to the expertise of tightrope walkers via prosthetic feedback [PDF]
Is the head more locked to the trunk or stabilised in space during quite stance? Does prosthetic vestibular feedback have a positive impact on movement strategies and muscle synergies of those with vestibular loss?
Honegger, Flurin
core +1 more source
Rethinking personhood and agency: how AI challenges human-centered concepts
Artificial intelligence (AI) systems increasingly display behaviors once thought to be exclusively human, prompting people to attribute intention, emotion, and even moral responsibility to these agents.
Lu Gao, Gustave Florentin Nkoulou Mvondo
doaj +1 more source
Report of Cerebellar Hypoplasia in Three Calves
Hereditary or acquired cerebellar hypoplasia (CH) is commonly diagnosed in Holstein, Guernsey, Shorthorn and Jersey cattle. Bovine viral diarrhea (BVD) has been associated to acquired CH due to viral infection during the second trimester of pregnancy ...
Daniela Junqueira de Queiroz +6 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Propositional Attitudes, Intentionality and Lawful Behaviors
This paper aims to discuss Quine’s last analysis of propositional attitudes as involving intentionality and as regards human action and the very subject matter of social sciences.
Luiz Henrique de A. Dutra
doaj
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
DOI: http://doi.org/10.26333/stsen.xxxi.04 The aim of this paper is to present and analyze arguments provided for the Psychological Principle of Non-Contradiction which states that one cannot have, or cannot be described as having, contradictory ...
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

