Results 121 to 130 of about 513,377 (289)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Battery State of Health Estimation Using the Sliding Interacting Multiple Model Strategy

open access: yesEnergies
Due to their nonlinear behavior and the harsh environments to which batteries are subjected, they require a robust battery monitoring system (BMS) that accurately estimates their state of charge (SOC) and state of health (SOH) to ensure each battery’s ...
Richard Bustos   +4 more
doaj   +1 more source

A Hybrid Land Conversion Model Incorporating Multiple End Uses

open access: yes
The need for models that forecast land use change spans many disciplines and encompasses many approaches. Pattern-based models were the first in which projections of change at specific locations in actual landscapes could be predicted.
Towe, Charles A., Ye, Xin, Kaza, Nikhil
core  

Emotional Modulation of Temporal Attention, An Approach based upon Distributed Control and Formal Methods [PDF]

open access: yes, 2006
This paper investigates how emotional salience modulates Barnard et al's key-distractor attentional blink task, enabling us to elucidate the temporal dynamics of attentional capture by emotional stimuli.
Barnard, Philip, Bowman, Howard, Li, Su
core  

A model for high-multiplicity πp interactions

open access: yesNuclear Physics B, 1969
Abstract The transition matrix element S for high multiplicity reactions πp → p+ (N − 1)π is assumed to depend only on the four-momentum transfer, t, from the initial to the secondary nucleon. A method of deriving the so-called F(t) function giving the empirical form of the averaged t-dependence of the matrix element for many-body processes is ...
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Interacting multiple model behavior-guided multi-model trajectory prediction for highly maneuverable aerial targets

open access: yesDiscover Applied Sciences
To address the challenge of trajectory prediction for highly maneuverable aerial targets, this paper introduces the novel Intention-guided Interactive Multiple Model (IGIMM) method. Following a “recognize-then-predict” approach, this model first performs
Panghe Qiu   +3 more
doaj   +1 more source

Tracking multiple point targets using genetic interacting multiple model based algorithm

open access: yes, 2004
Multiple point target tracking in the presence of dense clutter requires tracking maneuvering and non-maneuvering targets simultaneously in the absence of any apriori information about target dynamics. We propose a tracking algorithm based on interacting
DESAI, UB, MERCHANT, SN, ZAVERI, MA
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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