Results 121 to 130 of about 515,994 (291)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Tracking interacting targets in multi-modal sensors [PDF]

open access: yes, 2009
PhDObject tracking is one of the fundamental tasks in various applications such as surveillance, sports, video conferencing and activity recognition. Factors such as occlusions, illumination changes and limited field of observance of the sensor make ...
Taj, Murtaza
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Interacting Multiple Model Approach for Tracking13; Maneuvering Targets [PDF]

open access: yes, 2002
The Interacting Multiple Model (IMM) is a sub-optimal hybrid approach that has come to be recognized as one of the most cost-effective techniques for target tracking.
Singh, Jatinder, Kashyap, SK
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Emotional Modulation of Temporal Attention, An Approach based upon Distributed Control and Formal Methods [PDF]

open access: yes, 2006
This paper investigates how emotional salience modulates Barnard et al's key-distractor attentional blink task, enabling us to elucidate the temporal dynamics of attentional capture by emotional stimuli.
Barnard, Philip, Bowman, Howard, Li, Su
core  

Battery State of Health Estimation Using the Sliding Interacting Multiple Model Strategy

open access: yesEnergies
Due to their nonlinear behavior and the harsh environments to which batteries are subjected, they require a robust battery monitoring system (BMS) that accurately estimates their state of charge (SOC) and state of health (SOH) to ensure each battery’s ...
Richard Bustos   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Interacting multiple model behavior-guided multi-model trajectory prediction for highly maneuverable aerial targets

open access: yesDiscover Applied Sciences
To address the challenge of trajectory prediction for highly maneuverable aerial targets, this paper introduces the novel Intention-guided Interactive Multiple Model (IGIMM) method. Following a “recognize-then-predict” approach, this model first performs
Panghe Qiu   +3 more
doaj   +1 more source

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