Results 71 to 80 of about 15,858,106 (394)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Constraining anomalous Higgs interactions
The recently announced Higgs discovery marks the dawn of the direct probing of the electroweak symmetry breaking sector. Sorting out the dynamics responsible for electroweak symmetry breaking now requires probing the Higgs interactions and searching for ...
Corbett, Tyler+3 more
core +1 more source
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions [PDF]
Background: The modeling of interactions among transcription factors (TFs) and their respective target genes (TGs) into transcriptional regulatory networks is important for the complete understanding of regulation of biological processes.
Luiz A. Bovolenta+2 more
core +4 more sources
Next-Generation Sequencing for Binary Protein-Protein Interactions
The yeast two-hybrid (Y2H) system exploits host cell genetics in order to display binary protein-protein interactions (PPIs) via defined and selectable phenotypes.
Bernhard eSuter+6 more
doaj +1 more source
While considered an extracellular pathogen, Pseudomonas aeruginosa has been reported to be engulfed by macrophages in cellular and animal models. However, the role of macrophages in P. aeruginosa clearance in vivo remains poorly studied.
Malika Moussouni+4 more
doaj +1 more source
Game theory presumes that agents have unique preference orderings over outcomes that prescribe unique preference orderings over actions in response to other players' actions, independent of other players' preferences. This independence assumption is necessary to permit game-theoretic best response reasoning, but at odds with introspection, because ...
Nax, Heinrich H+2 more
openaire +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Phenomenological Lambda-Nuclear Interactions
Variational Monte Carlo calculations for ${_{\Lambda}^4}H$ (ground and excited states) and ${_{\Lambda}^5}He$ are performed to decipher information on ${\Lambda}$-nuclear interactions.
A. A. Usmani+32 more
core +2 more sources
High-energy neutrino-nucleus interactions [PDF]
High-energy neutrino-nucleus interactions are discussed by considering neutrino-oscillation experiments and ultra-high-energy cosmic neutrino interactions.
Kumano, S.
core +2 more sources
Learning to Detect Human-Object Interactions [PDF]
We study the problem of detecting human-object interactions (HOI) in static images, defined as predicting a human and an object bounding box with an interaction class label that connects them.
Yu-Wei Chao+4 more
semanticscholar +1 more source