Results 71 to 80 of about 10,494,319 (348)

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Seed tuber imprinting shapes the next-generation potato microbiome

open access: yesEnvironmental Microbiome
Background Potato seed tubers are colonized and inhabited by soil-borne microbes, that can affect the performance of the emerging daughter plant in the next season.
Yang Song   +7 more
doaj   +1 more source

Next-Generation Sequencing for Binary Protein-Protein Interactions

open access: yesFrontiers in Genetics, 2015
The yeast two-hybrid (Y2H) system exploits host cell genetics in order to display binary protein-protein interactions (PPIs) via defined and selectable phenotypes.
Bernhard eSuter   +6 more
doaj   +1 more source

Thermodynamic curvature measures interactions

open access: yes, 2010
Thermodynamic fluctuation theory originated with Einstein who inverted the relation $S=k_B\ln\Omega$ to express the number of states in terms of entropy: $\Omega= \exp(S/k_B)$.
Arfken G. B.   +8 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Interactive preferences [PDF]

open access: yesEconomics Letters, 2015
Game theory presumes that agents have unique preference orderings over outcomes that prescribe unique preference orderings over actions in response to other players' actions, independent of other players' preferences. This independence assumption is necessary to permit game-theoretic best response reasoning, but at odds with introspection, because ...
Nax, Heinrich H   +2 more
openaire   +4 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Neutrino interactions with nuclei

open access: yes, 2009
We present a model for neutrino-nucleus scattering in the energy region relevant for present and forthcoming neutrino-oscillation experiments. The model is based on the RPA treatment of the nuclear responses in the quasi-elastic and Delta-resonance ...
Federico Sanchez   +6 more
core   +3 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Shared features and reciprocal complementation of the Chlamydomonas and Arabidopsis microbiota

open access: yesNature Communications, 2022
Plants and algae associate with microbial communities that affect their growth and development. Here, the authors characterize the microbiota associated with a unicellular alga in soil, revealing extensive taxonomic and functional overlap with the root ...
Paloma Durán   +7 more
doaj   +1 more source

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