RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Network Analysis to Identify MicroRNAs Involved in Alzheimer's Disease and to Improve Drug Prioritization. [PDF]
Reyna A, Panni S.
europepmc +1 more source
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
In silico interactome analysis reveals distinct and complementary metabolic roles of bacteria in stingless bee larval food. [PDF]
de Avila NB +5 more
europepmc +1 more source
MAVISp: A modular structure‐based framework for protein variant effects
Abstract The role of genomic variants in disease has expanded significantly with the advent of advanced sequencing techniques. The rapid increase in identified genomic variants has led to many variants being classified as Variants of Uncertain Significance or as having conflicting evidence, posing challenges for their interpretation and ...
Matteo Arnaudi +32 more
wiley +1 more source
Abstract Non‐vesicular lipid transport contributes to the regulation of membrane composition and organelle function at membrane contact sites. OSBP‐related proteins (ORPs) are central to this process, yet their interaction networks remain incompletely defined. Here, we systematically screened potential interactions between ORPs and phosphoinositide 3‐,
Filippo Dall'Armellina +2 more
wiley +1 more source
Co-Immunoprecipitation-Coupled Mass Spectrometry Analysis of Zyxin's Interactome and Phosphosites in Early Xenopus laevis Development. [PDF]
Parshina EA +3 more
europepmc +1 more source
Alphafuser: a parsimonious approach to predicting higher‐order protein complexes
Alphafuser is a structure‐prediction pipeline that integrates experimental interaction data with AlphaFold‐based modeling to systematically assemble multiprotein complexes in a computationally efficient manner. By implementing an ipTM‐based pruning algorithm and validating against known structures and experimental assays, Alphafuser enables the ...
Audrey Guillotin +5 more
wiley +1 more source
Myoferlin is a component of late-stage vRNP trafficking vesicles for enveloped RNA viruses. [PDF]
Bonazza S +11 more
europepmc +1 more source

