Results 191 to 200 of about 63,382 (353)
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a genetic disorder of the myocardium. Mutations in the PKP2, DSP, DSG2, DSC2, JUP, TMEM43, PLN and DES genes which encode proteins of the cardiac desmosome have been linked to the disease yet, the
Athanasios Balaskas +5 more
doaj +1 more source
Social Interactome Recommender Project
Contains a Word document and PDF of the final report, and the Powerpoint and PDF for our final presentation.Our team is working with the Social Interactome team to assist in coding the recommender functionality for the Social Interactome network. That is
Gray, Colin +2 more
core
The +1 interaction network for the 52 GWAS genes with intermediate and high significance ...
David B. Sattelle (347392) +8 more
core +1 more source
Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu +13 more
wiley +1 more source
Predicting Oxidative Stress Interactome of Sperm
First interactome study of sperm.
Burak Ozkosem (441153)
core +1 more source
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang +7 more
wiley +1 more source
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley +1 more source
Human protein interactome induced by first quasi-biclique QB1.
The interactome consists of 120 human proteins and 509 interactions among them. The density of the interactome is nearly 0.07.
Ujjwal Maulik (169015) +1 more
core +1 more source
Huntingtin as an Actin Organizer: Structural and Functional Insights
Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley +1 more source
The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu +6 more
wiley +1 more source

