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Intercalated Cells: More than pH Regulation [PDF]
The renal collecting duct is the nephron segment where the final urine content of acid equivalents and inorganic ions are determined. The role of two different cell types present in this nephron segment has been determined many years ago: principal cells
Ensaf Y. Almomani +3 more
doaj +2 more sources
Anatomical Connectivity of the Intercalated Cells of the Amygdala. [PDF]
AbstractThe intercalated cells of the amygdala (ITCs) are a fundamental processing structure in the amygdala that remain relatively understudied. They are phylogenetically conserved from insectivores through primates, inhibitory, and project to several of the main processing and output stations of the amygdala and basal forebrain.
Stern DB, Wilke A, Root CM.
europepmc +5 more sources
A Comparative Kidney Transcriptome Analysis of Bicarbonate-Loaded insrr-Null Mice
The maintenance of plasma pH is critical for life in all organisms. The kidney plays a critical role in acid–base regulation in vertebrates by controlling the plasma concentration of bicarbonate. The receptor tyrosine kinase IRR (insulin receptor-related
E. A. Gantsova +6 more
doaj +1 more source
Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney
Background: Several members of the SLC26A family of transporters, including SLC26A3 (DRA), SLC26A5 (prestin), SLC26A6 (PAT-1; CFEX) and SLC26A9, form multi-protein complexes with a number of molecules (e.g., cytoskeletal proteins, anchoring or adaptor ...
Jie Xu +12 more
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Apical intercalated cell cluster: A distinct sensory regulator in the amygdala
Summary: GABAergic neurons regulate different aspects of information processing in the amygdala. Among these are clusters of intercalated cells (ITCs), which have been implicated in fear-related behaviors.
Douglas Asede +6 more
doaj +1 more source
Cell intercalation from top to bottom [PDF]
Animal development requires a carefully orchestrated cascade of cell fate specification events and cellular movements. A surprisingly small number of choreographed cellular behaviours are used repeatedly to shape the animal body plan. Among these, cell intercalation lengthens or spreads a tissue at the expense of narrowing along an orthogonal axis. Key
Elise, Walck-Shannon, Jeff, Hardin
openaire +2 more sources
Ferritin is the main intracellular storage of iron. Animal studies show that female liver and kidney express more ferritin and accumulate more iron than male. However, no study so far has investigated sex and age differences in light (FtL) and heavy (FtH)
Vulinović Mirela Pavić +3 more
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p63+ ureteric bud tip cells are progenitors of intercalated cells. [PDF]
During renal branching morphogenesis, ureteric bud tip cells (UBTC) serve as the progenitor epithelium for all cell types of the collecting duct. While the transcriptional circuitry of ureteric bud (UB) branching has been intensively studied, the transcriptional control of UBTC differentiation has been difficult to ascertain.
El-Dahr SS +8 more
europepmc +4 more sources
Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice
The UDP-glucose receptor P2RY14, a rhodopsin-like G protein-coupled receptor (GPCR), was previously described as receptor expressed in A-intercalated cells of the mouse kidney.
Fabian Baalmann +10 more
doaj +1 more source
Urinary Tract Infections: Renal Intercalated Cells Protect against Pathogens.
Urinary tract infections affect more than 1 in 2 women during their lifetime. Among these, more than 10% of patients carry antibiotic-resistant bacterial strains, highlighting the urgent need to identify alternative treatments.
Chelangarimiyandoab F +3 more
europepmc +3 more sources

