Novel Proinflammatory Function of Renal Intercalated Cells [PDF]
Annals of Nutrition and Metabolism, 2018 <b><i>Background:</i></b> Serious and often fatal acute kidney injury (AKI) is frequently seen after major surgery, local and remote organ damage, and sepsis. It is associated with uncontrolled inflammation, and is usually diagnosed only after the kidneys have gone through significant and often irreversible damage.
Sylvie, Breton, Dennis, Brown
openaire +2 more sources
Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy [PDF]
, 2013 BACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function.
Benz, PM +35 more
core +1 more source
Cell biology of the intercalated cell in the kidney [PDF]
FEBS Letters, 2013 The intercalated cell of the collecting tubule of the mammalian kidney is specialized for the transport of H+ and HCO3. They exist in two forms; one specialized for acid secretion and the other secretes HCO3 into the urine. We discovered many years ago that feeding animals an acid diet converts the HCO3 secreting form to an acid secreting type.
openaire +2 more sources
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts
eLife, 2017 Although most nephron segments contain one type of epithelial cell, the collecting ducts consists of at least two: intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively.
Max Werth +17 more
doaj +1 more source
Proliferation of acid-secretory cells in the kidney during adaptive remodelling of the collecting duct. [PDF]
PLoS ONE, 2011 The renal collecting duct adapts to changes in acid-base metabolism by remodelling and altering the relative number of acid or alkali secreting cells, a phenomenon termed plasticity.
Desa Welsh-Bacic +3 more
doaj +1 more source
Intercalated cells of the rat inner medullary collecting duct [PDF]
, 1987 Intercalated cells of the rat inner medullary collecting duct. There is increasing evidence of acidification along the entire mammalian collecting duct including the inner medullary collecting duct (IMCD).
Tisher, C.Craig +3 more
core +1 more source
mCCDcl1 cells exhibit a transitional phenotype: implications for collecting duct plasticity [PDF]
, 2018 The cortical collecting duct of the mammalian kidney plays a critical role in the regulation of body volume, sodium pH and osmolarity and is composed of two distinct cells types, principal cells and intercalated cells.
Assmus, Adrienne Madeleine
core +3 more sources
Applied Microscopy, 2020 Arthropods have an open circulatory system with a simple tubular heart, so it has been estimated that the contractile pumping structure of the cardiac muscle will be less efficient than that of vertebrates.
Yan Sun +3 more
doaj +1 more source
Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]
, 2013 Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T. +12 more
core +2 more sources
Frontiers in Neural Circuits, 2012 In the amygdala, GABAergic neurons in the intercalated medial paracapsular cluster (Imp) have been suggested to play a key role in fear learning and extinction. These neurons project to the central amygdaloid nucleus and to other areas within and outside
Raffaella eGeracitano +4 more
doaj +1 more source