Renal Intercalated Cells: Alien Cells Inside Us? [PDF]
BiologyMammalian renal intercalated cells are known for their role in acid secretion and maintaining acid–base balance. Herein, we discuss the theoretical reasons behind their development based on published data, focusing on the unique characteristics of renal ...
Miguel Luis Graciano
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Renal intercalated cells and blood pressure regulation [PDF]
Kidney Research and Clinical Practice, 2017 Type B and non-A, non-B intercalated cells are found within the connecting tubule and the cortical collecting duct. Of these cell types, type B intercalated cells are known to mediate Cl⁻ absorption and HCO₃⁻ secretion largely through pendrin-dependent ...
Susan M. Wall
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Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli [PDF]
Nature Communications, 2021 Kidney intercalated cells are involved in acid-base homeostasis in the kidneys. Here, the authors use single cell transcriptomics and find that interalated cells exhibit a transcriptional response conducive to defense and can engulf and acidify ...
Vijay Saxena +10 more
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The Renal Physiology of Pendrin-Positive Intercalated Cells. [PDF]
Physiol Rev, 2020 Intercalated cells (ICs) are found in the connecting tubule and the collecting duct. Of the three IC subtypes identified, type B intercalated cells are one of the best characterized and known to mediate Cl−absorption and HCO3−secretion, largely through the anion exchanger pendrin.
Wall SM, Verlander JW, Romero CA.
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Anatomical Connectivity of the Intercalated Cells of the Amygdala. [PDF]
eNeuro, 2023 AbstractThe intercalated cells of the amygdala (ITCs) are a fundamental processing structure in the amygdala that remain relatively understudied. They are phylogenetically conserved from insectivores through primates, inhibitory, and project to several of the main processing and output stations of the amygdala and basal forebrain.
Stern DB, Wilke A, Root CM.
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Sulfatide with ceramide composed of phytosphingosine (t18:0) and 2-hydroxy FAs in renal intercalated cells [PDF]
Journal of Lipid Research, 2022 Diverse molecular species of sulfatide with differences in FA lengths, unsaturation degrees, and hydroxylation statuses are expressed in the kidneys. However, the physiological functions of specific sulfatide species in the kidneys are unclear.
Keiko Nakashima +15 more
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MAP3K7 is an innate immune regulatory gene with increased expression in human and murine kidney intercalated cells following uropathogenic Escherichia coli exposure. [PDF]
J Cell Biochem, 2022 Understanding the mechanisms responsible for the kidney's defense against ascending uropathogen is critical to devise novel treatment strategies against increasingly antibiotic resistant uropathogen.
Saxena V +4 more
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Deletion of ErbB4 Disrupts Synaptic Transmission and Long-Term Potentiation of Thalamic Input to Amygdalar Medial Paracapsular Intercalated Cells [PDF]
Frontiers in Synaptic Neuroscience, 2021 Identification of candidate risk genes and alteration in the expression of proteins involved in regulating inhibitory neuron function in various psychiatric disorders, support the notion that GABAergic neuron dysfunction plays an important role in ...
Douglas Asede +4 more
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p63+ ureteric bud tip cells are progenitors of intercalated cells. [PDF]
JCI Insight, 2017 During renal branching morphogenesis, ureteric bud tip cells (UBTC) serve as the progenitor epithelium for all cell types of the collecting duct. While the transcriptional circuitry of ureteric bud (UB) branching has been intensively studied, the transcriptional control of UBTC differentiation has been difficult to ascertain.
El-Dahr SS +8 more
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No Zoom Required: Meeting at the β-Intercalated Cells. [PDF]
J Am Soc Nephrol, 2020 Lin WY, Muallem S.
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