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Differentiation of Intercalated Cells in the Kidney

Physiology, 2011
The intercalated cell of collecting ducts of the kidney is of two forms, the α form secretes acid, whereas the β form secretes HCO3. Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.
Qais, Al-Awqati, Xaio Bo, Gao
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Differentiation of intercalated cells in culture

Pediatric Nephrology, 1993
The renal collecting duct is a heterogenous epithelium consisting of intercalated cells (ICCs) and principal cells (PCs). To test the hypothesis that the two cell types might originate from one another and to determine which one of the two is a stem cell, beta-ICCs and PCs were isolated by fluorescence-activated cell sorting and grown on permeable ...
G, Fejes-Tóth, A, Náray-Fejes-Tóth
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Metals intercalated in graphite. V. A concentration cell with intercalated bromine

Canadian Journal of Chemistry, 1976
Bromine intercalates can be used as electrodes in concentration cells. Voltages of the order of 50 mV can be obtained with thermal gradients of 60–75 °C, in the range 0–100 °C. The cell can be operated on a continuous basis by allowing the high activity electrode to distill bromine to the low activity electrode.
Jean-Marc Lalancette, Roger Roussel
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The intercalated cells of the amygdala

Journal of Comparative Neurology, 1986
AbstractThe intercalated cell groups, or massa intercalata, of the amygdala have been studied in rodent brains with Golgi methods. They also have been examined in gallocyanin‐chromalum‐, AChE‐, and Timm‐stained rat brains.The Golgi data indicate that the intercalated cells are not confined to a series of isolated cell clumps but form a neuronal net ...
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Phenotypic plasticity in the intercalated cell: the hensin pathway

American Journal of Physiology-Renal Physiology, 1998
The collecting duct of the renal tubule contains two cell types, one of which, the intercalated cell, is responsible for acidification and alkalinization of urine. These cells exist in a multiplicity of morphological forms, with two extreme types, α and β.
Q, Al-Awqati   +4 more
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Function and Regulation of Collecting Duct Intercalated Cells

Annual Review of Physiology, 1993
Renal intercalated cells (IC) are interspersed among the segment-specific majority (principal) cells of the distal convoluted tubule, connecting tubule, and collecting duct (71, 144). Ultrastructurally, ICs are distinguished by their dark cytoplasm, high mitochondrial density, cytoplasmic tubulovesicular structures, and apical microprojections (87 ...
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Novel insights in the regulation of intercalated cell differentiation

Current Opinion in Nephrology & Hypertension
Purpose of review Kidney intercalated cells play critical roles in regulating body acid–base balance. We recently discovered Foxp1 and two downstream transcriptional factors Dmrt2 and Hmx2 are essential for intercalated cell differentiation.
Yu, Feng, Yanmiao, Qi, Xiangjian, Zheng
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Recent advances in our understanding of intercalated cells

Current Opinion in Nephrology & Hypertension, 2005
This review will summarize newly described novel functions of renal intercalated cells.Over the past 20 years, the importance of intercalated cells in the process of renal net acid excretion has been recognized. More recently, many of the molecular mechanisms responsible for this cellular function have been described.
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Mathematical modeling of intercalation batteries at the cell level and beyond

Chemical Society Reviews, 2013
Mathematical modeling of lithium ion batteries is a key feature for a profound understanding of the whole spectrum of phenomena occurring in such electrochemical systems. Due to their inherent multi-scale nature, batteries cannot be described with a single equation.
Landstorfer, M., Jacob, T.
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