Results 21 to 30 of about 10,129 (256)
Transition Metal Intercalators as Anticancer Agents—Recent Advances [PDF]
International Journal of Molecular Sciences, 2016 The diverse anticancer utility of cisplatin has stimulated significant interest in the development of additional platinum-based therapies, resulting in several analogues receiving clinical approval worldwide. However, due to structural and mechanistic similarities, the effectiveness of platinum-based therapies is countered by severe side-effects ...
Deo, Krishant M. (S32272) +4 more
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Electrochemical Biosensors for Detection of MicroRNA as a Cancer Biomarker: Pros and Cons
Biosensors, 2020 Cancer is the second most fatal disease in the world and an early diagnosis is important for a successful treatment. Thus, it is necessary to develop fast, sensitive, simple, and inexpensive analytical tools for cancer biomarker detection.
Maliana El Aamri +4 more
doaj +1 more source
AN INSIGHT INTO MEDICINAL PROPERTIES OF QUINOXALINE SCAFFOLD, WITH A FOCUS ON THEIR ANTICANCER POTENTIAL AS INTERCALATING AGENTS [PDF]
Al-Azhar Journal of Pharmaceutical SciencesThe antitumor properties of synthetic heterocyclic compounds are among the most important properties that can be made use in medicinal chemistry. More specifically, their significant cytotoxic effects against many types of human tumor cells, as well as ...
Mohammed Dahab +3 more
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WikiJournal of Medicine, 2018 Anthracyclines are a clinically important class of antineoplastic agents used to treat a wide variety of solid and blood cancers. The first described anthracycline, daunorubicin, was first isolated from a strain of Streptomyces peucetius in the early ...
Alison Cheong +2 more
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From a Co-Mo precursor to 1H and 1T Co-promoted MoS2: exploring the effects of gas pressure
Frontiers in Physics, 2023 The work presented in this paper makes use of the high-pressure in situ imaging capabilities of the ReactorSTM to demonstrate that single layer 1T Co-promoted MoS2 can be directly synthesized without the use of any intercalating agents by applying highly
M. K. Prabhu, I. M. N. Groot
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Topoisomerases inhibition and DNA binding mode of daunomycin–oligoarginine conjugate
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Cancer is a major health issue adsorbing the attention of a biomedical research. To fight this disease, new drugs are developed, specifically tailored to target biological pathways or peculiar components of the tumour cells.
Valeria Visone +5 more
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Genetics and Molecular Biology, 2014 The genotoxicity of bloom head (BHE) and leaf (LE) extracts from artichoke (Cynara scolymus L.), and their ability to modulate the mutagenicity and recombinogenicity of two alkylating agents (ethyl methanesulfonate - EMS and mitomycin C - MMC) and the ...
Laura Vicedo Jacociunas +6 more
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Pharmaceuticals, 2020 This work showcased the first physicochemical investigation of psoralen (PSO) binding to double stranded DNA (dsDNA) through electroanalytical methods. Results evidenced that PSO presents one non-reversible anodic peak at electric potential (Epa) ≈ 1.42 ...
Douglas Vieira Thomaz +4 more
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Rapid Synthesis of Kaolinite Nanoscrolls through Microwave Processing
Nanomaterials, 2022 Kaolinite nanoscrolls (NScs) are halloysite-like nanotubular structures of great interest due to their ability to superimpose halloysite’s properties and applicability.
Md Shahidul Islam Khan, John B. Wiley
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Effect of Intercalation Agents on Morphology of Exfoliated Kaolinite [PDF]
Minerals, 2017 Kaolinite intercalation compounds were prepared by intercalating fatty acids and quaternary ammonium salts into kaolinite layers, using methanol-grafted kaolinite as the precursor. Meanwhile, massive lamellas were exfoliated during the intercalation process.
Xiaochao Zuo +4 more
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