Results 201 to 210 of about 4,686,959 (289)
Emerging pathological mechanisms of Alzheimer's disease pathogenesis: from neuroimmune interactions to intercellular communication. [PDF]
Wang R +8 more
europepmc +1 more source
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao +12 more
wiley +1 more source
Mitochondrial Network Dynamics in Aging: Cellular Mechanisms, Intercellular Communication, and Their Impact on Tissue Adaptability. [PDF]
Labusca L, Gheorghevici TS, Puha B.
europepmc +1 more source
An environmentally responsive antenna assembled onto the algal cell membrane creates a biohybrid with a responsive interface that promotes photosynthesis under normal conditions and shifts to H2O2‐triggered stress reporting and modulation upon stress onset, boosting environmental sensing and adaptive response.
Bing Liu +6 more
wiley +1 more source
Decoding Alzheimer's genetic risk through intercellular communication in the human brain: Lessons from Clusterin. [PDF]
Lish AM, Young-Pearse TL.
europepmc +1 more source
Intercellular communication in the kidney [PDF]
openaire +1 more source
Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang +7 more
wiley +1 more source
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
Exploring the Spatial Limits of Extracellular Vesicles-Mediated Intercellular Communication. [PDF]
Colombo F +4 more
europepmc +1 more source

