Mitochondrial DNA-Mediated Intercellular Communication via Extracellular Vesicles Under Hypoxic Stress to Drive HCC Progression. [PDF]
Fu J +7 more
europepmc +1 more source
Quantum Nanomedicine and Quantum Biomaterials
In this perspective, we define quantum nanomedicine and quantum biomaterials as a paradigm that harnesses quantum effects in nanomedicine and biomaterials, including quantum superposition, quantum coherence, quantum tunneling, topological quantum effects, and spin polarization, to achieve either spatiotemporally precise modulation of physiological ...
Xinyue Dai +3 more
wiley +1 more source
A Primer on Proteomic Characterization of Intercellular Communication in a Virus Microenvironment. [PDF]
Kostas JC, Brainard CS, Cristea IM.
europepmc +1 more source
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
Single-cell multiome characterizing intercellular communication and intracellular regulation of epithelium and mesenchymal during secondary palate development in mice. [PDF]
Hussein U +6 more
europepmc +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
NEU1-Mediated Extracellular Vesicle Glycosylation in Alzheimer's Disease: Mechanistic Insights into Intercellular Communication and Therapeutic Targeting. [PDF]
Adnan M +5 more
europepmc +1 more source
A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
wiley +1 more source

