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CONNEXINS, CONNEXONS, AND INTERCELLULAR COMMUNICATION
Annual Review of Biochemistry, 1996Cells in tissues share ions, second messengers, and small metabolites through clusters of intercellular channels called gap junctions. This type of intercellular communication permits coordinated cellular activity. Intercellular channels are formed from two oligomeric integral membrane protein assemblies, called connexons, which span two adjacent ...
David L Paul +2 more
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Classical and Nonclassical Intercellular Communication in Senescence and Ageing [PDF]
[Abstract] Intercellular communication refers to the different ways through which cells communicate with each other and transfer a variety of messages.
Ana O'Loghlen
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Intercellular communication for innate immunity
Molecular Immunology, 2017An effective innate immune response relies on the detection of pathogen associated molecular patterns (PAMPs) by various host pattern recognition receptors (PRRs) that result in the production of pro-inflammatory cytokines and chemokines. Viruses and bacteria have co-evolved with the immune system and developed multiple strategies to usurp or ...
Tan A, Nguyen +2 more
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Defective gap junctional intercellular communication in the carcinogenic process [PDF]
Gap junctions are membrane structures made of intercellular channels which permit the diffusion from cytoplasm to cytoplasm of small hydrophilic molecules.
Marc Mesnil
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Cell junctions and intercellular communication
In Vitro, 1980We have compared intercellular communication in normal and regenerating rat liver. Gap junctions are greatly reduced in size and numbers 29 to 35 hr after hepatectomy, but we still find some 90% of hepatocytes coupled by electrophysiological criteria.
J P, Revel +3 more
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Intercellular Communication and Bladder Function
2003There is now considerable experimental and clinical evidence supporting the supposition that overactivity of the bladder is associated with detectable alterations in the electrical properties of the detrusor smooth muscle cells. The preliminary data described in this report indicates that intercellular communication through gap junctions might play an ...
George J, Christ +8 more
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Intercellular communication in smooth muscle
Experientia, 1992The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for cell heterogeneity within smooth muscle tissues has renewed research into cell coupling.
Huizinga, J.D. +4 more
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Contactomics of Microglia and Intercellular Communication
Microglia represent the main immunocompetent cell type in the parenchyma of the brain and the spinal cord, with roles extending way beyond their immune functions. While emerging data show the pivotal role of microglia in brain development, brain health and brain diseases, the exact mechanisms through which microglia contribute to complex neuroimmune ...Cserép, Csaba +3 more
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[Intercellular communication].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2000There are 3 modalities for intercellular communications: the chemical substances secreted by some cells are transported at distance where they act as signals on other cells; the surface molecules of a group of cells interact with the neighbouring cells; some special junctions or nexus provide direct relations between cells.
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Intercellular Communication and Cancer
1977Among the several different forms of cell interactions known to exist in multicellular organisms intercellular communication provides the most direct form of communication by allowing free exchange of ions and small molecules between neighboring cells via permeable membrane junctions. This type of communication has been implicated in various biological
Roobik Azarnia, William J. Larsen
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