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Intercellular Communication in the Heart: Therapeutic Opportunities for Cardiac Ischemia [PDF]
The maintenance of tissue, organ, and organism homeostasis relies on an intricate network of players and mechanisms that assist in the different forms of cell–cell communication.
Tania Martins-Marques +2 more
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Defective gap junctional intercellular communication in the carcinogenic process
Gap junctions are membrane structures made of intercellular channels which permit the diffusion from cytoplasm to cytoplasm of small hydrophilic molecules.
Marc Mesnil
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CONNEXINS, CONNEXONS, AND INTERCELLULAR COMMUNICATION
Annual Review of Biochemistry, 1996Cells in tissues share ions, second messengers, and small metabolites through clusters of intercellular channels called gap junctions. This type of intercellular communication permits coordinated cellular activity. Intercellular channels are formed from two oligomeric integral membrane protein assemblies, called connexons, which span two adjacent ...
Daniel A Goodenough, David L Paul
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We recently reported that tumor necrosis factor is able to cause a dose-dependent and persistent reduction in gap junctional intercellular communication between primary human smooth muscle cells.
A Brouwer
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Intercellular communication for innate immunity
Molecular Immunology, 2017An effective innate immune response relies on the detection of pathogen associated molecular patterns (PAMPs) by various host pattern recognition receptors (PRRs) that result in the production of pro-inflammatory cytokines and chemokines. Viruses and bacteria have co-evolved with the immune system and developed multiple strategies to usurp or ...
Tan A, Nguyen +2 more
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Cell junctions and intercellular communication
In Vitro, 1980We have compared intercellular communication in normal and regenerating rat liver. Gap junctions are greatly reduced in size and numbers 29 to 35 hr after hepatectomy, but we still find some 90% of hepatocytes coupled by electrophysiological criteria.
J P, Revel +3 more
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Intercellular Communication and Bladder Function
2003There is now considerable experimental and clinical evidence supporting the supposition that overactivity of the bladder is associated with detectable alterations in the electrical properties of the detrusor smooth muscle cells. The preliminary data described in this report indicates that intercellular communication through gap junctions might play an ...
George J, Christ +8 more
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Oscillatory dynamics in intercellular communication.
Biomedica biochimica acta, 1990info:eu-repo/semantics ...
Goldbeter, Albert +2 more
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Microplatform for intercellular communication
2008 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2008A microplatform was designed, fabricated, and tested for demonstrating the propagation of molecular signals through a line of patterned HeLa cells expressing gap junction channels (HeLa Cx43 cells). The microplatform was capable of patterning cells onto a predefined design with lithography and surface chemical treatment.
null Tadashi Nakano +7 more
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[Intercellular communication].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2000There are 3 modalities for intercellular communications: the chemical substances secreted by some cells are transported at distance where they act as signals on other cells; the surface molecules of a group of cells interact with the neighbouring cells; some special junctions or nexus provide direct relations between cells.
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