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Intercellular communication for innate immunity

Molecular Immunology, 2017
An effective innate immune response relies on the detection of pathogen associated molecular patterns (PAMPs) by various host pattern recognition receptors (PRRs) that result in the production of pro-inflammatory cytokines and chemokines. Viruses and bacteria have co-evolved with the immune system and developed multiple strategies to usurp or ...
Tan A, Nguyen   +2 more
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CONNEXINS, CONNEXONS, AND INTERCELLULAR COMMUNICATION

Annual Review of Biochemistry, 1996
Cells in tissues share ions, second messengers, and small metabolites through clusters of intercellular channels called gap junctions. This type of intercellular communication permits coordinated cellular activity. Intercellular channels are formed from two oligomeric integral membrane protein assemblies, called connexons, which span two adjacent ...
D A, Goodenough, J A, Goliger, D L, Paul
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Intercellular Communication Route?

Science, 2004
Mammalian cells interact with one another in a variety of ways, for example, by secreting and binding diffusible messengers like hormones and growth factors, or between attached cells via gap junctions. Rustom et al. now describe what may represent an independent form of cell-cell communication that they term ...
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Intercellular communication in smooth muscle

Experientia, 1992
The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for cell heterogeneity within smooth muscle tissues has renewed research into cell coupling.
Huizinga, J.D.   +4 more
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Cell junctions and intercellular communication

In Vitro, 1980
We have compared intercellular communication in normal and regenerating rat liver. Gap junctions are greatly reduced in size and numbers 29 to 35 hr after hepatectomy, but we still find some 90% of hepatocytes coupled by electrophysiological criteria.
J P, Revel   +3 more
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[Intercellular communication].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2000
There are 3 modalities for intercellular communications: the chemical substances secreted by some cells are transported at distance where they act as signals on other cells; the surface molecules of a group of cells interact with the neighbouring cells; some special junctions or nexus provide direct relations between cells.
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Microplatform for intercellular communication

2008 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2008
A microplatform was designed, fabricated, and tested for demonstrating the propagation of molecular signals through a line of patterned HeLa cells expressing gap junction channels (HeLa Cx43 cells). The microplatform was capable of patterning cells onto a predefined design with lithography and surface chemical treatment.
null Tadashi Nakano   +7 more
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Intercellular Communication and Bladder Function

2003
There is now considerable experimental and clinical evidence supporting the supposition that overactivity of the bladder is associated with detectable alterations in the electrical properties of the detrusor smooth muscle cells. The preliminary data described in this report indicates that intercellular communication through gap junctions might play an ...
George J, Christ   +8 more
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Intercellular Communication and Cancer

1977
Among the several different forms of cell interactions known to exist in multicellular organisms intercellular communication provides the most direct form of communication by allowing free exchange of ions and small molecules between neighboring cells via permeable membrane junctions. This type of communication has been implicated in various biological
Roobik Azarnia, William J. Larsen
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Intercellular Communication Through Microtubular Highways

Tunneling nanotubes (TNTs) are open-ended, membrane-encased extensions that connect neighboring cells. They have diameters up to 1 μm but are able to expand to convey large cargos. Lengths vary depending on the distance of the cells but have been reported to be capable of extending beyond 300 μm.
Lorél Y, Medina, Rita E, Serda
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