Results 31 to 40 of about 160,421 (276)

RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system [PDF]

open access: yes, 2012
ATP-dependent paracrine signaling, mediated via the release of ATP through plasma membrane-embedded hemichannels of the connexin family, coordinates a synchronized response between neighboring cells.
Bultynck, Geert   +7 more
core   +3 more sources

Understanding Multicellularity: The Functional Organization of the Intercellular Space [PDF]

open access: yes, 2019
The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration,
Bich, Leonardo   +2 more
core   +10 more sources

NcRNAs in Vascular and Valvular Intercellular Communication

open access: yesFrontiers in Molecular Biosciences, 2021
Non-coding RNAs have been shown to be important biomarkers and mediators of many different disease entities, including cardiovascular (CV) diseases like atherosclerosis, aneurysms, and valvulopathies. Growing evidence suggests a central role of ncRNAs as
Benedikt Bartsch   +9 more
doaj   +1 more source

Context-aware deconvolution of cell–cell communication with Tensor-cell2cell

open access: yesNature Communications, 2022
Cellular contexts such as disease state, organismal life stage and tissue microenvironment, shape intercellular communication, and ultimately affect an organism’s phenotypes.
Erick Armingol   +6 more
doaj   +1 more source

Finite-State Channel Models for Signal Transduction in Neural Systems

open access: yes, 2016
Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W.   +2 more
core   +1 more source

Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]

open access: yes, 1982
Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J.   +3 more
core   +2 more sources

Loss and reappearance of gap junctions in regenerating liver [PDF]

open access: yes, 1978
Changes in intercellular junctional morphology associated with rat liver regeneration were examined in a freeze-fracture study. After a two-thirds partial hepatectomy, both gap junctions and zonulae occludentes were drastically altered.
Revel, J.-P., Yee, A. G.
core   +2 more sources

Antitumor Immunity: Role of NK Cells and Extracellular Vesicles in Cancer Immunotherapy

open access: yesCurrent Issues in Molecular Biology, 2023
The immune system plays a crucial role in recognizing and eliminating altered tumor cells. However, tumors develop mechanisms to evade the body’s natural immune defenses. Therefore, methods for specifically recognizing/targeting tumor cells, for instance,
Angelina E. Prokopeva   +2 more
doaj   +1 more source

Modeling Cell-to-Cell Communication Networks Using Response-Time Distributions. [PDF]

open access: yes, 2018
Cell-to-cell communication networks have critical roles in coordinating diverse organismal processes, such as tissue development or immune cell response. However, compared with intracellular signal transduction networks, the function and engineering
Altschuler, Steven J   +2 more
core   +2 more sources

7-Ketocholesterol modulates intercellular communication through gap-junction in bovine lens epithelial cells

open access: yesCell Communication and Signaling, 2004
Background Connexin43 (Cx43) is an integral membrane protein that forms intercellular channels called gap junctions. Intercellular communication in the eye lens relies on an extensive network of gap junctions essential for the maintenance of lens ...
Pereira Paulo   +2 more
doaj   +1 more source

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