Results 51 to 60 of about 4,686,959 (289)
Journal of Biomechanical Science and Engineering, 2009 Intracellular calcium ([Ca2+]i) is a second messenger molecule critical for numerous intracellular signaling pathways in endothelial cells (ECs). Direct mechanical stimulation imposed on single ECs by a microprobe has been demonstrated to increase [Ca2 ...
Susumu KUDO +4 more
doaj +1 more source
TRIM22 induces cellular senescence by targeting PHLPP2 in hepatocellular carcinoma
Cell Death and DiseaseThe ubiquitin-proteasome system is a vital protein degradation system that is involved in various cellular processes, such as cell cycle progression, apoptosis, and differentiation.
Donghee Kang +8 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Fine intercellular connections in development: TNTs, cytonemes, or intercellular bridges?
Cell Stress, 2020 Intercellular communication is a fundamental property of multicellular organisms, necessary for their adequate responses to changing environment. Tunneling nanotubes (TNTs) represent a novel means of intercellular communication being a long cell-to-cell ...
Olga Korenkova +2 more
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Biochemistry and Biophysics Reports, 2023 Fibroblast is the critical repair cell for urethral wound healing. The dysfunction of fibroblasts can lead to excessive fibrosis and hypertrophic scar, which eventually leads to post-traumatic urethral stricture. However, the fibroblast subpopulation and
Kuiqing Li +5 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Exosomes and Ectosomes in Intercellular Communication [PDF]
Current Biology, 2018 Exosomes and ectosomes, two distinct types of extracellular vesicles generated by all types of cell, play key roles in intercellular communication. The formation of these vesicles depends on local microdomains assembled in endocytic membranes for exosomes and in the plasma membrane for ectosomes.
openaire +2 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Intercellular Nanotubes Mediate Bacterial Communication [PDF]
Cell, 2011 Bacteria are known to communicate primarily via secreted extracellular factors. Here we identify a previously uncharacterized type of bacterial communication mediated by nanotubes that bridge neighboring cells. Using Bacillus subtilis as a model organism, we visualized transfer of cytoplasmic fluorescent molecules between adjacent cells.
Dubey GP, Ben-Yehuda S
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Intercellular communication in phytohemagglutinin - induced lymphocyte agglutinates [PDF]
, 1971 Intercellular communication, as indicated by ion flow between cells, was measured with micro-glass-electrodes in lymphocytes immediately after addition of ...
J. H. Peters +3 more
core +1 more source