Results 71 to 80 of about 4,686,959 (289)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication

Cell Communication and Signaling, 2023
Extracellular vesicles (EVs) are small, membrane-bound structures that are released from cells into the surrounding environment. These structures can be categorized as exosomes, microvesicles, or apoptotic vesicles, and they play an essential role in ...
Ya-Juan Liu, Cheng Wang
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Intercellular Communication, Homeostasis, and Toxicology [PDF]

Toxicological Sciences, 2002
The article highlighted in this issue is "Inhibition of Gap Junctional Intercellular Communication by Perfluorinated Compounds in Rat Liver and Dolphin Kidney Epithelial Cell Lines in Vitro and Sprague-Dawley Rats in Vivo" by W. Hu, P. D. Jones, B. L. Upham, J. E. Trosko, C. Lau, and J. P. Giesy (pp. 429-436).
openaire   +2 more sources

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Migrasomes, critical players in intercellular communication

Cancer Cell International
Migrasomes are a newly discovered type of extracellular vesicle (EV) formed during cell migration, playing a pivotal role in intercellular communication.
Zhiyong Tan, Chadanfeng Yang, Shi Fu, Junchao Wu, Yinglong Huang, Haihao Li, Chen Gong, Dihao Lv, Jiansong Wang, Mingxia Ding, Haifeng Wang   +10 more
doaj   +1 more source

Fas signalling promotes intercellular communication in T cells. [PDF]

PLoS ONE, 2012
Cell-to-cell communication is a fundamental process for development and maintenance of multicellular organisms. Diverse mechanisms for the exchange of molecular information between cells have been documented, such as the exchange of membrane fragments ...
Francesca Luchetti, Barbara Canonico, Marcella Arcangeletti, Michele Guescini, Erica Cesarini, Vilberto Stocchi, Mauro Degli Esposti, Stefano Papa   +7 more
doaj   +1 more source

Biomimetic Core–Shell Liposome Nanoparticles Deplete Lipoproteins and Enhance the Purity of Extracellular Vesicles from Human Blood

Advanced Functional Materials, EarlyView.
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang, Andrew J. Perciaccante, David Inman, Bong Hwan Sung, Alissa M. Weaver, Suzanne M. Ponik, Ying Ge, Song Jin   +7 more
wiley   +1 more source

The Marshall Islands : history, culture and communication [PDF]

, 1980
"Draft: Not for Quotation, Citation or Reproduction without Permission of Author."For more about the East-West Center, see https://www.eastwestcenter.org/Policy decisions about communication system resources are an important part of controlled ...
Runeborg, Ruth E., East-West Communication Institute   +1 more
core   +1 more source

OrganiZational communication and organiSational communication: Binaries and the fragments of a field [PDF]

, 2009
In this paper, I employ personal narrative to help cast light on connections and tensions between organiZational communication research, as produced in the United States, and organiSational communication research, as produced in Aotearoa New Zealand.
Ganesh, Shiv
core