Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. [PDF]
, 2020 Male factor infertility is a problem in today's society but many underlying causes are still unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) knockout mouse line (SCCx43KO) has provided a translational model ...
Behr, Rüdiger +10 more
core +1 more source
Migrasomes, a new mode of intercellular communication
Cell Communication and Signaling, 2023 Migrasomes are newly discovered extracellular vesicles (EVs) that are formed in migrating cells and mediate intercellular communication. However, their size, biological generation, cargo packaging, transport, and effects on recipient cells by migrasomes ...
Yuyun Jiang +6 more
doaj +1 more source
Connecting different heart diseases through intercellular communication
Biology Open, 2021 Well-orchestrated intercellular communication networks are pivotal to maintaining cardiac homeostasis and to ensuring adaptative responses and repair after injury. Intracardiac communication is sustained by cell–cell crosstalk, directly via gap junctions
Tania Martins-Marques
doaj +1 more source
RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system [PDF]
, 2012 ATP-dependent paracrine signaling, mediated via the release of ATP through plasma membrane-embedded hemichannels of the connexin family, coordinates a synchronized response between neighboring cells.
Bultynck, Geert +7 more
core +3 more sources
Understanding Multicellularity: The Functional Organization of the Intercellular Space [PDF]
, 2019 The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration,
Bich, Leonardo +2 more
core +11 more sources
NcRNAs in Vascular and Valvular Intercellular Communication
Frontiers in Molecular Biosciences, 2021 Non-coding RNAs have been shown to be important biomarkers and mediators of many different disease entities, including cardiovascular (CV) diseases like atherosclerosis, aneurysms, and valvulopathies. Growing evidence suggests a central role of ncRNAs as
Benedikt Bartsch +9 more
doaj +1 more source
Connexin-dependent neuroglial networking as a new therapeutic target [PDF]
, 2017 Astrocytes and neurons dynamically interact during physiological processes, and it is now widely accepted that they are both organized in plastic and tightly regulated networks.
Christian C. Naus +5 more
core +2 more sources
Context-aware deconvolution of cell–cell communication with Tensor-cell2cell
Nature Communications, 2022 Cellular contexts such as disease state, organismal life stage and tissue microenvironment, shape intercellular communication, and ultimately affect an organism’s phenotypes.
Erick Armingol +6 more
doaj +1 more source
Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]
, 1982 Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J. +3 more
core +2 more sources
Finite-State Channel Models for Signal Transduction in Neural Systems
, 2016 Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W. +2 more
core +1 more source