The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. [PDF]
, 1997 Oleamide is a sleep-inducing lipid originally isolated from the cerebrospinal fluid of sleep-deprived cats. Oleamide was found to potently and selectively inactivate gap junction-mediated communication between rat glial cells.
Cao +35 more
core +2 more sources
Regulation of gap junctions by protein phosphorylation
Brazilian Journal of Medical and Biological Research, 1998 Gap junctions are constituted by intercellular channels and provide a pathway for transfer of ions and small molecules between adjacent cells of most tissues.
J.C. Sáez +3 more
doaj +1 more source
Diet-dependent immunohistochemical evaluation of connexin 43 in the sheep rumen [PDF]
, 2016 The objective of this study was to characterize the immunohistochemical localization of plasma membrane connexin 43 in the rumen of sheep after changing the diet from hay (ad libitum) to a mixed hay/concentrate diet.
Ahmed, Rasha S. +2 more
core +1 more source
Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]
, 1982 Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J. +3 more
core +2 more sources
Nonlinear gap junctions enable long-distance propagation of pulsating calcium waves in astrocyte networks [PDF]
PLoS Comput Biol 6(8): e1000909, 2010 A new paradigm has recently emerged in brain science whereby communications between glial cells and neuron-glia interactions should be considered together with neurons and their networks to understand higher brain functions. In particular, astrocytes, the main type of glial cells in the cortex, have been shown to communicate with neurons and with each ...
arxiv +1 more source
Connexins: synthesis, post-translational modifications, and trafficking in health and disease [PDF]
, 2018 Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate direct intercellular communication, a critical feature for the development, function, and homeostasis of tissues and organs.
Aasen, Trond +5 more
core +3 more sources
Cell Communication and Signaling, 2004 Background Connexin43 (Cx43) is an integral membrane protein that forms intercellular channels called gap junctions. Intercellular communication in the eye lens relies on an extensive network of gap junctions essential for the maintenance of lens ...
Pereira Paulo +2 more
doaj +1 more source
The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on $\textrm{Ca}^{2+}$ dynamics [PDF]
, 2020 Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a substantial loss of $\beta$-cell mass and alteration of $\beta$-cell function in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. The mechanisms for deficiency in $\beta$-cell mass and function during the hyperglycemia development and T2D ...
arxiv +1 more source
Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength [PDF]
, 2002 By tethering intermediate filaments (IFs) to sites of intercellular adhesion, desmosomes facilitate formation of a supercellular scaffold that imparts mechanical strength to a tissue.
Amargo, Evangeline V. +11 more
core +4 more sources
The Dynamics of Sustained Reentry in a Loop Model with Discrete Gap Junction Resistance [PDF]
Phys. Rev. E. 76, 021928 (2007), 2007 Dynamics of reentry are studied in a one dimensional loop of model cardiac cells with discrete intercellular gap junction resistance ($R$). Each cell is represented by a continuous cable with ionic current given by a modified Beeler-Reuter formulation. For $R$ below a limiting value, propagation is found to change from period-1 to quasi-periodic ($QP$)
arxiv +1 more source