Results 51 to 60 of about 665,109 (406)

Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface

Veterinary Research, 2019
Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists of epithelial cells closely connected by intercellular junctions, selective gates which control paracellular diffusion of solutes, ions ...
Tingting Cui, Sebastiaan Theuns, Jiexiong Xie, Hans J. Nauwynck   +3 more
doaj   +1 more source

Interaction Studies Between Cyclic Peptide ADT-C3 (Ac-CADTPC-NH2) with E-Cadherin Protein using the Molecular Docking Method Simulated on 120ns

Jurnal Kimia Sains dan Aplikasi, 2018
The treatment of diseases that attack the brain is very difficult, because the delivery of drug molecules to the brain is often hindered by the blood-brain barrier (BBB). So that the drug delivery is not right on the target cell.
Parsaoran Siahaan, Vivitri Dewi Prasasty, Atiatul Manna, Dwi Hudiyanti   +3 more
doaj   +1 more source

Protective effects of HBOC on pulmonary vascular leakage after haemorrhagic shock and the underlying mechanisms

Artificial Cells, Nanomedicine, and Biotechnology, 2020
Volume resuscitation is an important early treatment for haemorrhagic shock. Haemoglobin-based oxygen carrier (HBOC) can expand the volume and provide oxygen for tissues.
Hong Liang Zhao, Jie Zhang, Yu Zhu, Yue Wu, Qing Guang Yan, Xiao Yong Peng, Xin Ming Xiang, Kun Lun Tian, Tao Li, Liang Ming Liu   +9 more
doaj   +1 more source

Computing the Threshold of the Influence of Intercellular Nanotubes on Cell-to-Cell Communication Integrity [PDF]

, 2015
We examine the threshold of the influence of the tunneling nanotubes (TNTs) on the cell-to-cell communication integrity. A deterministic model is introduced with the Michaelis-Menten dynamics and the intercellular exchange of substance. The influence of TNTs are considered as a functional perturbation of the main communication and treated as the matrix
arxiv   +1 more source

Effects of reduced discrete coupling on filament tension in excitable media [PDF]

, 2011
Wave propagation in the heart has a discrete nature, because it is mediated by discrete intercellular connections via gap junctions. Although effects of discreteness on wave propagation have been studied for planar traveling waves and vortexes (spiral ...
Alonso, Sergio, Bar, Markus, Panfilov, Alexander   +2 more
core   +4 more sources

Biotin-cGMP and -cAMP are able to permeate through the gap junctions of some amacrine cells in the mouse retina despite their large size

Frontiers in Ophthalmology
Gap junctions transmit electrical signals in neurons and serve metabolic coupling and chemical communication. Gap junctions are made of intercellular channels with large pores, allowing ions and small molecules to permeate.
Chunxu Yuan, Luca Gerhards, Ilia A. Solov’yov, Ilia A. Solov’yov, Ilia A. Solov’yov, Karin Dedek, Karin Dedek   +6 more
doaj   +1 more source

ATP Release from Cultured Endothelial Cells and Intercellular Calcium Signaling during Shear Stress Exposure

Journal of Biomechanical Science and Engineering, 2009
Intracellular calcium ([Ca2+]i) is a second messenger molecule critical for numerous intracellular signaling pathways in endothelial cells (ECs). Direct mechanical stimulation imposed on single ECs by a microprobe has been demonstrated to increase [Ca2 ...
Susumu KUDO, Kaoru HOSOE, Makoto HOSOBUCHI, Naoto KAWASAKI, Kazuo TANISHITA   +4 more
doaj   +1 more source

Optimality of intercellular signaling: direct transport versus diffusion [PDF]

, 2022
Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of signaling molecules and direct transport mediated by signaling cellular protrusions.
arxiv   +1 more source

Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]

, 2017
The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino, Trepat Guixer, Xavier   +1 more
core   +4 more sources

PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus

Scientific Reports, 2023
Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes.
Abbey L. Perl, Jennifer L. Koetsier, Kathleen J. Green   +2 more
doaj   +1 more source