Results 31 to 40 of about 81,400 (215)

Organ crosstalk benefits during exercise [PDF]

Journal of Exercise & Organ Cross Talk
Dear Editor-in-ChiefWe are writing to highlight the significant benefits of organ crosstalk during exercise, a phenomenon that refers to the biochemical interactions among various tissues stimulated by different factors, with exercise being a prominent ...
Alexei Wong, Hossein Shirvani
doaj   +1 more source

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]

, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core   +1 more source

Identification of Quorum-Sensing Inhibitors Disrupting Signaling between Rgg and Short Hydrophobic Peptides in Streptococci

mBio, 2015
Bacteria coordinate a variety of social behaviors, important for both environmental and pathogenic bacteria, through a process of intercellular chemical signaling known as quorum sensing (QS).
Chaitanya Aggarwal, Juan Cristobal Jimenez, Hyun Lee, George E. Chlipala, Kiira Ratia, Michael J. Federle   +5 more
doaj   +1 more source

Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins. [PDF]

, 2017
The identification of conserved autophagy-related proteins (ATGs) that mediate bulk degradation of cytosolic material laid the foundation for breakthroughs linking autophagy to a litany of physiological processes and disease conditions.
Cadwell, Ken, Debnath, Jayanta
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficacy of Concentrated Growth Factors in Treating Tympanic Membrane Perforation in Guinea Pigs

Journal of International Advanced Otology
Background: Less invasive and cost-effective alternatives are needed to manage tympanic membrane perforation (TMP). Therefore, the effectiveness of concentrated growth factors (CGF) in promoting tympanic membrane regeneration in guinea pig models of ...
Takahiro Hanari, Masahiro Okada, Takahiro Nakata, Sawa Asoh, Eriko Nishihara, Masato Teraoka, Naohito Hato   +6 more
doaj   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Baumert M., Bittner M. A., Bittner M. A., Bittner M. A., Blasi J., Elferink L. A., Fischer G., Geppert M., Halpern J. L., Hess S. D., Jahn R., MANFRED GRATZL, Marqueze-Pouey B., McMahon H. T., Schiavo G., Schiavo G., Schiavo G., Schmidle T., Shirataki H., Shoji-Kasai Y., Stecher B., Thomas L., Trimble W. S., Walch-Solimena C., Wright J. F., Yoshida A.   +28 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Neuron-to-glia and glia-to-glia signaling directs critical period experience-dependent synapse pruning

Frontiers in Cell and Developmental Biology
Experience-dependent glial synapse pruning plays a pivotal role in sculpting brain circuit connectivity during early-life critical periods of development.
Nichalas Nelson, Vanessa Miller, Kendal Broadie, Kendal Broadie, Kendal Broadie, Kendal Broadie, Kendal Broadie   +6 more
doaj   +1 more source

Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings [PDF]

Characterization of disease-associated proteins improves our understanding of disease pathophysiology. Obtaining a comprehensive coverage of the proteome is challenging, mainly due to limited statistical power and an inability to verify hundreds of ...
Borràs, Daniel M., Frantzi, Maria, Jankowski, Vera, Janssen, Bart, Latosinska, Agnieszka, Makridakis, Manousos, Merseburger, Axel S., Mischak, Harald, Mullen, William, Vlahou, Antonia, Zoidakis, Jerome   +10 more
core   +1 more source