Connexin mimetic peptides reversibly inhibit Ca2+ signaling through gap junctions in airway cells
The effect of peptides with sequences derived from connexins, the constituent proteins of gap junctions, on mechanically stimulated intercellular Ca(2+) signaling in tracheal airway epithelial cells was studied.
Boitano, Scott, Evans, William Howard
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The translational relevance of the Annexin A1 pathway in inflammatory pathologies: opportunities for novel therapeutic development [PDF]
PhDEndogenous anti-inflammatory mediators form a complex network triggered in the host to dampen cell activation and promote resolution of inflammation.
Dalli, Jesmond
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Elucidation of a molecular mechanism controlling inflammation during bacterial infection [PDF]
Recently we described a mechanism of gap junction-mediated communication between infected and uninfected epithelial cells that potentiates innate immunity during infection by the enteroinvasive bacterium Shigella flexneri.
Tschon, Therese
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CLE peptide signaling during plant development [PDF]
Peptide signaling in plants is a rapid developing area of research which focuses on so called peptide hormones. These signaling molecules are utilized for inter-cellular communication in different developmental processes, beside the usage of the more ...
Fiers, M.A. +3 more
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Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms [PDF]
Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this ...
Susanna C. Fagerholm +11 more
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Storage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies [PDF]
Contains fulltext : 109602.pdf (Publisher’s version ) (Open Access)Physiological erythrocyte removal is associated with a selective increase in expression of neoantigens on erythrocytes and their vesicles, and subsequent autologous ...
Dinkla, S. +19 more
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Host protein phosphorylation during "Shigella flexneri" infection : a phosphoproteomic based systems biology approach [PDF]
The enteroinvasive bacterium Shigella flexneri triggers its uptake into epithelial cells by injecting several effector proteins via its type three secretion system (TTSS) and interferes with various host cell processes at later stages of infection.
Schmutz, Christoph
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Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Bettina Kempf +17 more
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LuxI and LuxR are key factors that drive quorum sensing (QS) in bacteria through secretion and perception of the signaling molecules e.g. N-Acyl homoserine lactones (AHLs).
Akanksha Rajput, Manoj Kumar
doaj +1 more source
Expressions of Transforming Growth Factor β1 Signaling Cytokines in Aortic Dissection
Objective: To demonstrate the underlying mechanisms of aortic dissection compared to those of coronary artery disease in terms of the transforming growth factor-beta (TGF-β) signaling pathway.
Shi-Min Yuan, Hong Lin
doaj +1 more source

