Results 31 to 40 of about 49,064 (119)

Neuron-to-glia and glia-to-glia signaling directs critical period experience-dependent synapse pruning

Frontiers in Cell and Developmental Biology
Experience-dependent glial synapse pruning plays a pivotal role in sculpting brain circuit connectivity during early-life critical periods of development.
Nichalas Nelson, Vanessa Miller, Kendal Broadie, Kendal Broadie, Kendal Broadie, Kendal Broadie, Kendal Broadie   +6 more
doaj   +1 more source

Amplifying the innate immune response : cell-cell propagation of proinflammatory signals during bacterial infection [PDF]

, 2012
The enteroinvasive bacterium Shigella flexneri uses multiple secreted effector proteins to downregulate interleukin-8 (IL-8) expression in infected epithelial cells. Nevertheless, massive IL-8 secretion is observed in shigellosis. In this thesis, a novel
Kasper, Christoph Alexander
core   +1 more source

The isolation and characterisation of MHC-presented peptides from CML-derived cell-lines, with a focus on post-translational modification [PDF]

, 2011
Phosphorylation is a key regulator of protein function and activity, and aberrant kinase activity is implicated in a wide range of malignancies, of which the bcr:abl fusion kinase found in chronic myeloid leukaemia is a classic example.
Kapoor, KN
core  

Connexin mimetic peptides reversibly inhibit Ca²⁺signaling through gap junctions in airway cells

, 2000
The effect of peptides with sequences derived from connexins, the constituent proteins of gap junctions, on mechanically stimulated intercellular Ca2+signaling in tracheal airway epithelial cells was studied.
Scott Boitano, W. Howard Evans
core   +1 more source

TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia [PDF]

, 2010
Background: Staphylococcus epidermidis (SE) is a nosocomial pathogen that causes catheter-associated bacteremia in the immunocompromised, including those at the extremes of age, motivating study of host clearance mechanisms. SE-derived soluble components
Gallington, LC, Levy, O., Stoler-Barak Liat, Currie, A.J., Golenbock Douglas T., Golenbock, D.T., Melanie R Power Coombs, Otto, M, Gallington, Leighanne C., Burgner David, Levy, Ofer, Power Coombs, Melanie R., Richmond Peter, Currie, AJ, Douglas T Golenbock, Andrew J Currie, Power Coombs, M.R., Gallington, L.C., Strunk, Tobias, Stoler-Barak, L, Burgner, D., Burgner, D, Leighanne C Gallington, Golenbock, DT, Otto, Michael, Power Coombs Melanie R., Otto Michael, Currie, Andrew J., Richmond, P., Levy Ofer, Ofer Levy, Strunk Tobias, Otto, M., Liat Stoler-Barak, Tobias Strunk, Stoler-Barak, L., Burgner, David, Currie Andrew J., Richmond, Peter, Levy, O, Strunk, T, David Burgner, Coombs, MRP, Stoler-Barak, Liat, Peter Richmond, Strunk, T., Michael Otto, Richmond, P, Golenbock, Douglas T., Gallington Leighanne C.   +49 more
core   +2 more sources

The Proteomic and Peptidomic Response of Wheat (Triticum aestivum L.) to Drought Stress

Plants
Drought conditions impact plants at the morphological, physiological, and molecular levels. Plant tolerance to drought conditions is frequently associated with maintaining proteome stability, highlighting the significance of proteomic analysis in ...
Regina Azarkina, Arina Makeeva, Anna Mamaeva, Sergey Kovalchuk, Daria Ganaeva, Igor Tikhonovich, Igor Fesenko   +6 more
doaj   +1 more source

Teneurin evolution and brain-specific functions [PDF]

, 2012
Teneurins are a novel family of type II transmembrane proteins. They are highly conserved from invertebrates to vertebrates, in which four paralogs exist, called teneurin-1 to -4.
Beckmann, Jan
core   +1 more source

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Zimmermann, Wolfgang, Grunert, Fritz, Watt, Suzanne M., Kuijpers, Taco W., Nagel, Gerhard, Thompson, John A.   +5 more
core   +2 more sources

Extracellular heat shock proteins in cell signaling [PDF]

, 2007
Extracellular stress proteins including heat shock proteins (Hsp) and glucose regulated proteins (Grp) are emerging as important mediators of intercellular signaling and transport.
Salamatu S. Mambula, Mambula, Salamatu S., Gray, Philip J., Jimmy R. Theriault, Theriault, Jimmy R., Philip J. Gray, Stuart K. Calderwood, Calderwood, Stuart K.   +7 more
core   +1 more source

Roles of small peptides encoded by non-coding RNAs in tumor invasion and migration

Frontiers in Pharmacology
Non-coding RNAs (ncRNAs), which are usually considered not to encode proteins, are widely involved in important activities including signal transduction and cell proliferation.
Jie Liu, Jie Liu, Xiyue Chang, Xiyue Chang, Laeeqa Manji, Zhijie Xu, Wan’an Xiao   +6 more
doaj   +1 more source