Results 41 to 50 of about 49,064 (119)

Investigation into the role of annexin 1 in the microcirculation of annexin 1 knockout mice [PDF]

open access: yes, 2005
PhDGlucocorticoids are used therapeutically for their anti-inflammatory and immunosuppressive actions. One of the ways they produce their potent effects is via regulation of the anti-inflammatory protein Annexin I (ANX-AI; 37 kDa protein).
Chatterjee, Bristi Emma
core   +4 more sources

Structural characterization of the leukemia drug target ABL kinase and unfolded polypeptides by novel solution NMR techniques [PDF]

open access: yes, 2010
Novel weak alignment techniques and new biochemical strategies like selective isotope labeling in combination with other high-resolution solution NMR methods have been applied to characterize folded and unfolded polypeptides.
Vajpai, Navratna
core   +1 more source

Collagen in the central nervous system: contributions to neurodegeneration and promise as a therapeutic target

open access: yesMolecular Neurodegeneration
The extracellular matrix is a richly bioactive composition of substrates that provides biophysical stability, facilitates intercellular signaling, and both reflects and governs the physiological status of the local microenvironment.
Lauren K. Wareham   +4 more
doaj   +1 more source

The role of chemistry and strut porosity and the influence of serum proteins in modulating cellular response to bone graft substitutes [PDF]

open access: yes, 2015
The objective of this thesis was to investigate the role of hydroxyapatite and silicate-substituted hydroxyapatite synthetic bone graft substitute (SBG) material properties in modulating the processes of protein adsorption and desorption, and their ...
Castagna, Viviana
core   +3 more sources

Structural Feature of Lipid Scrambling Model Transmembrane Peptides: Same-Side Positioning of Hydrophilic Residues and Their Deeper Position

open access: yes, 2020
Phospholipid scramblases that catalyze lipid transbilayer movement are associated with intercellular signaling and lipid homeostasis. Although several studies have shown that the hydrophilic residue-rich groove of the proteins mediates lipid scrambling ...
Minoru Nakano (1500658)   +9 more
core   +1 more source

Characterisation of the structural motifs Involved in the cleavage and secretion of human angiotensin-converting enzyme [PDF]

open access: yes, 2014
Includes bibliographical references.Angiotensin converting enzyme is an ectoprotein prone to regulated proteolytic solubilisation by an as yet unknown protease or sheddase.
Conrad, Nailah
core   +1 more source

Regulation of horizontal gene transfer by intercellular peptide signaling in Bacillus subtilis [PDF]

open access: yes, 2006
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2006."February 2006."Includes bibliographical references.Horizontal gene transfer plays an important role in bacterial evolution.
Auchtung, Jennifer M
core  

Src Family Tyrosine Kinase Signaling in Mouse and Human Embryonic Stem Cells [PDF]

open access: yes, 2013
Embryonic stem (ES) cells are derived from the inner cell mass of the blastocyst stage embryo and are characterized by self-renewal and pluripotency. Previous work has implicated the Src family of protein-tyrosine kinases (SFKs) in the self-renewal and ...
Zhang, Xiong
core  

Enhanced bioethanol production by Zymomonas mobilis in response to the quorum sensing molecules AI-2 [PDF]

open access: yes, 2011
The depletion of non-renewable energy resources, the environmental concern over the burning of fossil fuels, and the recent price rises and instability in the international oil markets have all combined to stimulate interest in the use of fermentation ...
Yang, Jung Woo, YANG, JUNG,WOO
core  

Cell-cell signaling during Dictyostelium development

open access: yes, 1998
Specific proteins and peptides, as well as cAMP, are used as intercellular signals in Dictyostelium. Our understanding of the signal transduction pathways activated by these signals has been expanded by inclusion of newly characterized proteins.
Söderbom, Fredrik,, Loomis, W F
core   +1 more source

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